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1、乌苯美司对消化道癌症化疗患者生活质量及免疫功能影响的比较中国临床康复第8卷第29期2004?10-15出版ChineseIoumatD,ClinicalRehabilitation,October152004Vo1.8No.29乌苯美司对消化道癌症化疗患者生活质量及免疫功能影响的比较吴瑾,周红凤,王翠华,隋广杰6299?临床研究?☆吴瑾,周红凤,王翠华,隋广杰,哈尔滨医科大学附属肿瘤医院内科,黑龙江省哈尔滨市150040吴瑾☆.女,1963年生,黑龙江省哈尔滨市人,汉族,哈尔滨医科大学在读博士,副主任医师,副教授,主要从事肿瘤性疾病的诊断,治疗方面的研究.XianUiu@public.hr.h
2、1.cn电话:+86-451-88637888中圈分类号:R73文献标识码:A文章编号:1671—5926(2004)29—6299—03收稿日期:2004—05—19修回日期:2004—08—05(24/GS)ComparisonoftheeffectsofubenimexonqualityoflifeandimmunefunctioninpatientswithdigestivetractcancerthroughchemotherapyJinWuHang-FengZhouCui-HuaWangOuang-JieSUiJinWuHang-FengZhouCui-HuaWangOuang-J
3、ieSui,DepartmentofInternalMedicine.AffihatedTumorHospitalofHarbinMedicalUniversity.Harbin150040,HeilongjiangProvince,ChinaJinWu☆.Fernale,HtinNationality,Bornin1963inHarbinCity,Hei-longjiangProvince,China,StudyinginHarbinMedicalUniversityfordoctor-ate,Associatechiefphysician,Associateprofessor.Resear
4、chdirection:di-ggnososandtherapyoftumorousdiseases.Xianiliu@public.hr.hi.cnTelephone:+86-451-88637888Received:2004—05—19Accepted:2004—08—05AbstractAⅡ:T0studytheclinicaleffectofubenimexinimprovingpostoperativeimmunologicalfunotioninpatientswitlldigestivetractcancerreceivingchemotherapy,a8wella8itsrol
5、esinimprovingthequalityoflife(QOL)ofpatients.M哐TH0DS:0nehundredandtwopatientswitlldigestivetractcancerwhohadaccessofialchemotherapyafteroperationwererandomlydividedintotreatmentgroup(n=51):receivingchemotherapyandoralubenimex(30mgperday)continuouslyfor6months;controlgroup(n=51):receiviflgonlysingleL
6、OHP-CF-5-Fucontinuouslyfor6cycles.ThenumberofTcellsub-group.theactivityofNKcellandIL-Haswella8theexpressionlevelofSIL2Rwerenleasuredwitllvenousbloodfromtinemptystomachbeforechemotherapy.atthe3and6cyclesofthechemotherapy.TlleQOLofpatientswasevaluatedaccordingtotheevalualtionsheetaboutKPSSCOreandthech
7、angeofbodymassaswellasQOLscaleofpatientsbeforechemotherapyandatthe6cycles.1uULTS:①I1lenumberofTcellsubgroup.theactivityofNKcellandIL-Ⅱa8wellastheexpressionlevelofSIL2Rinl~eatmentgroupaftertllreecycles
