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1、MolecularBioSystemsViewArticleOnlineREVIEWViewJournalViewIssueEvolutionarygametheory:moleculesasplayersabcdaefKatrinBohl,SabineHummert,SarahWerner,DavidBasanta,AndreasDeutsch,Citethis:Mol.BioSyst.,2014,aga10,3066StefanSchuster,Gu¨nterTheißenandAnjaSchroeterInthisan
2、danaccompanyingpaperwereviewtheuseofgametheoreticalconceptsincellbiologyandmolecularbiology.Thisreviewfocusesonthesubcellularlevelbyconsideringviruses,genes,andmoleculesasplayers.WediscussinwhichwaycatalyticRNAcanbetreatedbygametheory.Moreover,genescancompeteforsuc
3、cessinreplicationandcanhavedifferentstrategiesininteractionswithotherReceived20thDecember2013,geneticelements.Alsotransposableelements,or‘‘jumpinggenes’’,canactasplayersbecausetheyAccepted7thAugust2014usuallybeardifferenttraitsorstrategies.Virusescompeteinthecaseofco
4、-infectingahostcell.ProteinsDOI:10.1039/c3mb70601jinteractinagametheoreticalsensewhenformingheterodimers.Finally,wedescribehowtheShapleyvaluecanbeappliedtoenzymesinmetabolicpathways.Weshowthatgametheorycanbesuccessfullywww.rsc.org/molecularbiosystemsappliedtodescri
5、beandanalysescenariosatthemolecularlevelresultingincounterintuitiveconclusions.CreativeCommonsAttribution3.0UnportedLicence.1Introductioninteractionsamongcells.Inthefollowing,wereviewfuturepotentialareasaswellassuccessfulexamplesoftheapplicationTheapplicationofgame
6、theoryhasbeenextremelysuccessfulofgametheorytointeractionsamongmolecules.Weinterpretatthelevelofmulticellularorganisms,especiallytounderstandthisterminabroadsense,alsoincludingmacromolecular1–6animalbehaviour.Itsapplicationtocellularandsubcellularcomplexessuchasvir
7、uses.levelsoflifeismuchlesscommon,butofincreasinginterestNotonlyorganismsasawhole,butalsoallmacromoleculesthatandimportance.Wefeel,however,thatthepowerofrespectivehave(indirect)influenceontheirreproductivesuccesscanbeThisarticleislicensedunderaapproachesisstillseri
8、ouslyunderestimated.Tomotivatemoreconsideredasplayersinthesenseofgametheory.Manyoftheirresearcherstousethetoolsofgametheory,weoutlineitspropertie