Epi-LASIK保留角膜上皮瓣与弃除角膜上皮瓣术后临床结果与角膜形态的比较性分析

Epi-LASIK保留角膜上皮瓣与弃除角膜上皮瓣术后临床结果与角膜形态的比较性分析

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时间:2019-06-24

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1、天津医科大学硕士学位论文AbstractPurpose:Tocomparetheadvantagesanddisadvantagesofon-flapepipolislaserinsitukeratomileusis(Epi-LASIK)andoff-flapEpi—LASIK.Methods:Aprospectively,double-maskedandradomizedstudywasperformedon188eyesof94patients.Ineachpatient,oneeyeunderwenton—flapEpi—LASIK(on-flapgroup)andthefellowey

2、ehadoff-flapEpi—LASIK(off-flapgroup).Patientswereinstructedtoratetheirpainandotherdiscomfortablesymptomsonpostoperativeday1,2and3;visualacuity,refraction,Hazeformationandcornealtopographywereevaluated1monthand4monthspostoperatively.Results:1.Onpostoperativeday1,thedifferenceofsubjectivemeanpainwasno

3、tstatisticallysignificant(P=0.070):Onpostoperativeday2and3,thedifferencewerestatisticallysignificant(P=0.000and0.ooo).2.Onpostoperativeday1,2and3,thedifferencesbetweenthetwogroupsofphotophobiawereunstatisticalsignificant(P=0.455,0.736and0.085);onpostoperativeday1and2,thedifferencesbetweenthetwogroup

4、softearingwerenotstatisticalsignificant(仁0.506and0.149),andthedifferencesbetweeneyelidsweepalsowerenotstatisticalsignificant(P=0.366andO.740);onpostoperativeday3,thedifferencesoftearingandeyelidsweepwerestatisticalsignificant(P--0.001and0.028).3.ThemeanepithelialhealingtimeWas2.78±0.51daysintheon—fl

5、apgroupandWas2.34±0.52daysintheon—flapgroup(n=94).ThedifferenceWasnotstatisticallysignificant(尸三0.o18),Onthepostoperativeday7(n=74),77.03%ofeyeshadtransparentcomeasintheoff-flapgroupand41.41%intheon—flapgroup.4.Themeanuncorrectedvisualacuityonpostoperativeday7(n=74)was1.08±0.38intheon-flapgroupandwa

6、s1.17+0.35intheoff-flapgroup,thedifferenceWasnotstatisticallysignificant(卢O.215);ItWas1.24-1-0.34intheon—flapgroupandWas1.42±0.21inthefellowgroupat1monthpostoperatively(n=51),thedifferencewasstatisticallysignificant俨=0.000);Itwas1.42±O.21intheon-flapgroupandWas1.40±0.21intheoff-flapgroupat1monthpost

7、operatively(n=51),itWasnotsignificantdifferenct(P=0.485).III天津医科大学硕士学位论文5.At1month,themearlsphericalequivalentwasO.33±0.78Dand0.24±0.59Drangerespectively,at4months,theywere0.14±0.46DandO.18±0.50D,allt

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