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1、BarCharts,Inc.®WORLD’S#1QUICKREFERENCEGUIDEPharmacologyDrugFundamentals,PlustheMostFrequentlyPrescribedDrugClassifications—IncludingIndications,Reactions,Examples&MoredefinitionspharmacokineticspharmacodynamicsStudyofthemechanismsofactionofdrugswithinRoutesdrugstaketogetintothebodythe
2、bodyandhowdrugsproducetheireffectsinthebody•Enteral:pharmacogeneticsStudyofdrugreactionsinthebodythatareoEntersthebodythroughtheGItractunanticipatedorunusual,andmayhaveahereditarybasisfortheresponseoTakenbymouth,throughtherectum,underthetongueorheldinthecheekspharmacokineticsStudyofdr
3、ugactionsastheymovethroughthe•Parenteral:body;thewaythebodyabsorbs,distributes,metabolizesandexcretesoEntersthebodythroughadifferentmeans(i.e.,otherthantheGItract)drugs;mathematicalstudyofdrugsbasedontimeanddoseoCanbeinjectedintotheveins,arteries,muscles,spinalcord,orunderpharmacology
4、Studyofbiologicallyactivecompounds,howtheyreacttheskin;inhaledthroughthelungs;transdermallythroughtheskinviainthebodyandhowthebodyreactstothemointmentorpatchpharmacotherapeuticsStudyofdrugsusedtoprevent,treatorAbsorptiondiagnosedisease•BioavailabilityPercentabsorbedintosystemiccircula
5、tionafteradministrationpharmacyPreparationanddispensingofdrugsoBioavailabilitydependsonrouteofadministrationaswellasthetoxicologyStudyofharmfulorpoisonouseffectsofdrugsdrug’sabilitytocrossmembranesandreachitstargetoFirstPassEffect:nDrugsabsorbedthroughthestomachandsmallintestinemustpa
6、ssthroughtheliverbeforecirculatingsystemicallydrugnamesnLivercaninactivatethedrug,makinglessofthedrugavailabletoreachthetargetorganDRUG•Absorptionatcellularleveloccursthroughpassivetransport,activetransport,pinocytosisandfacilitateddiffusionDistributionChemicalNameGenericNameTradeName
7、•Influencedbyseveralfactors:ChemicalName:ScientificGenericDrug:Nonpro-BrandName:TradeoTissuepermeability:Abilityofdrugtopassthroughthemembranesname,describestheatomicprietaryname,abbreviationname,selectedbytherapidlyaffectstheextenttowhichthedrugmovesaroundinthebodyandmolecularstructu
8、reofo
