变应性鼻炎患病率及相关因素调查

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'变应性鼻炎患病率及相关因素调查'
中华q鼻flW喉头颈外科杂占 2011 年 3 月第46 卷第 3 期(:hin J Otorfiinoiaryngol HmH Neck Smx. Maivh 2011, Vol. 46, N\ 3 ■ 225 ??流行病学调查? 变应性鼻炎患病率及相关因素调查 王泽海林文森李书彦 赵绍成王丽 杨仲刚 陈杰 张振富 于金珍【摘要】目的 通过对变应性鼻炎(allergic rhinitis,AR)流行病学之大样本的调査,获得以农村 为主的AR的患病率及相关患病因素。方法2007年4月至2009年5月在河北省沧州市农村、渤海 湾黄骅市沿海渔村、承徳市雾灵山区、天津市区分别以行政乡、村和街道、居民小区等为单位,按行政 乡、村和街道、居民小区名册通过随机多级抽样和整群抽样抽取调査对象。然后按住户自然顺序,逐 一入户直接调査。同时按照自然数排序全部受调查人群,对每逢个位数0、1、5的受调查者抽取3 ~5 ml静脉血,由实验室专职人员做血清特异性IgE(specific IgE,sIgE)检测。采用SPSS 13.0软件对数 据进行统计学分析。结果本次流行病学调查对象共抽取5010人,其中有鼻变应性症状或体征者 823例(16. 4% )。进行血清slgE检测1576例,阳性402例(25. 5% ),其中146例合并有鼻变应性症 状或体征者确诊为AR,AR的患病率为9. 3% (146/1576)。不同年龄、职业、特应性体质以及有无鼻 部变应性症状人群之间slgE检测阳性率差异均有统计学意义(£值分别为7. 96、9. 73、16. 53、& 95, P值均< 0.05)。AR与支气管哮喘的发生呈正相关(回归系数3 =2. 544,P<0.01)o农村最常见的 变应原为狗上皮、猫上皮,城市最常见的变应原为屋尘螞、粉尘WL结论 AR的患病率无论在城市 还是在农村都比较髙?应受到重视,AR的发生与持应性休质、环境因素等有关。【关键词】流行病学研究;鼻炎,变应性,常年性;鼻炎,变应性,季节性;流行病学因素; 患病率;变应原Research on prevalence and related factors in allergic rhinitis WANG Ze-haia , UN Wen-sen. U Shu-yan, ZHAO Shao-cheng, WANG Li, YANG Zhong-gang, CHEN Jie, ZHANG Zhen-fu, YU Jin-zhen.? Department of Otorhinolaryngology Head and Neck Surgery、People's Hospital of Qingxian t Hebei Province t Qingxian 0626501 ChinaCorresponding author: WANG Ze-hai. Email: wx(/2324l6@ 163. com; UN Wen ? sen t Erruiil: chunrui36 @ hotmaiL com[Abstract] Objective To obtain the prevalence and related factors in allergic rhinitis ( AR) and other allergic diseases in niral area in China through epidemiological investigation with large sample and multi-faceted survey data? Methods Face to face survey was conducted in different regions( njral areas of Cangzhou, Hebeit coastal fishing village of Bohai Bayf anra of Wuling Mountain, Chen百de, urban areas of Tianjin) from April 2007 to May 2009.【n the same lime, serum specific lgE( slgE) waft detected in the digits of every 011 or 5 in lhem. SPSS 13. 0 software was used to analyze the data. Results Five thousand and ten cases were investigated. There were 823 cases with the symptoms or signs of AR ( 16. 4% ). Four hundred and two cases were found to have positive serum slgE antibody in 1576 detected cases (25. 5% )? One hundred and fourty-six cases with nasal allergic symptoms or signs were diagnosed as AR? The incidence of AR was 9. 3% ( 146/1576 )? The occurrence of allergic symptoms or signs had a significant statistical difference with factors such as age, occupationt atopic constitution ( \ value were 7.96. 9? 73, 16. 53,6 95 respectively, all P <0. 05) . and it was closely related to lower respiratory1 tract allergies ( B = 2. 544, P<0?01)? The most common allergens were dog and cat epithelium in rural areas and dust mites in city. Conclusions The incidence of AR is higher whether in urban or rural areas t it should be taken seriously as the impacl on human health? The occurrence is closely related to physical characteristics and environmental factors ?[Key words] Epidemiologic studies; Rhinitis9 allergic, perennial; Rhinitisallergicy seasonal; Epidemio
关 键 词:
变应性 鼻炎 患病 相关 因素 调查
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