冠状病毒Coronavirusl论文-2017 Seasonal Fluctuations of Astrovirus, But Not Coronavirus Shedding in Bats Inhabiting Human-Modified Tropical Forest.pdf

冠状病毒Coronavirusl论文-2017 Seasonal Fluctuations of Astrovirus, But Not Coronavirus Shedding in Bats Inhabiting Human-Modified Tropical Forest.pdf

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时间:2020-03-16

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1、EcoHealthDOI:10.1007/s10393-017-1245-xÓ2017EcoHealthAllianceOriginalContributionSeasonalFluctuationsofAstrovirus,ButNotCoronavirusSheddinginBatsInhabitingHuman-ModifiedTropicalForests1,23,43,43,4AnneSeltmann,VictorM.Corman,AndreaRasche,ChristianDrosten,5671,2Ga´borA´.Czir

2、ja´k,HenryBernard,MatthewJ.Struebig,andChristianC.Voigt1DepartmentofEvolutionaryEcology,LeibnizInstituteforZooandWildlifeResearch,Alfred-Kowalke-Str.17,10315Berlin,Germany2InstituteofBiology,FreieUniversita¨tBerlin,Takustr.3,14195Berlin,Germany3InstituteofVirology,Univer

3、sityofBonnMedicalCentre,Sigmund-Freud-Str.25,53127Bonn,Germany4GermanCentreforInfectionResearch,partnersiteBonn-Cologne,Bonn,Germany5DepartmentofWildlifeDiseases,LeibnizInstituteforZooandWildlifeResearch,Alfred-Kowalke-Str.17,10315Berlin,Germany6InstituteforTropicalBiolo

4、gyandConservation,UniversitiMalaysiaSabah,JalanUMS,88400KotaKinabalu,Sabah,Malaysia7DurrellInstituteofConservationandEcology(DICE),SchoolofAnthropologyandConservation,UniversityofKent,Canterbury,KentCT27NR,UKAbstract:Emerginginfectiousdiseases(EIDs)areconsideredamajorthr

5、eattoglobalhealth.MostEIDsappeartoresultfromincreasedcontactbetweenwildlifeandhumans,especiallywhenhumansencroachintoformerlypristinehabitats.Habitatdeteriorationmayalsonegativelyaffectthephysiologyandhealthofwildlifespecies,whichmayeventuallyleadtoahighersusceptibilityt

6、oinfectiousagentsand/orincreasedsheddingofthepa-thogenscausingEIDs.BatsareknowntohostvirusescloselyrelatedtoimportantEIDs.Here,wetestedinapaleotropicalforestwithongoingloggingandfragmentation,whetherhabitatdisturbanceinfluencestheoccurrenceofastro-andcoronavirusesineightb

7、atspecies.Incontrasttoourhypothesis,anthropogenichabitatdisturbancewasnotassociatedwithcorona-andastrovirusdetectionratesinfecalsamples.However,wefoundthatbatsinfectedwitheitherastro-orcoronaviruseswerelikelytobecoinfectedwiththerespectiveothervirus.Additionally,weidenti

8、fiedtwomoreriskfactorsinfluencingastrovirusshedding.First,thedetectionrateofastroviruseswashigheratthebeg

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