呼吸系统--组织学和胚胎学.ppt

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1、RespiratorysystemRespiratorysystemNasalcavity,pharynx&larynx.Trachea&bronchi.Lung.一、tracheamucosasubmucosaadventitiatrachea(HE)MixedglandEM:epitheliumoftrachea4.SmallgranuleC1.CiliatedC2.BrushC3.GobletC5.BasalCThewalloftrachea1.Mucosa=epithelium+laminapropri

2、apseudostratiatedciliatedcolumnar…CiliatedC,gobletC,brushC,basalC,smallgranularC.2.Submucosa=CT+mixedglands3.Adventitia=16-20‘C’shapedhaylinecartilagerings.atmosphere&alveolialveoli&blood(blood&tissue)Gasexchangebronchiolelunglung二、lungLungLowpowerlungparenc

3、hyma:bronchialtrees&alveoli.Principalbronchi(Br)—lobular、segmentalBr—smallerBr—bronchiole—terminalbronchiole—respiratorybronchiole—alveolarduct、alveolarsac—alveoli.Conductionportion:aboveterminalbronchioles.Respiratoryportion:respiratorybronchioletoalveoli.P

4、ulmonarylobule:bronchioleandit’sramifications.Conductionportion－lobularBr&smallBrEpitheliumGobletCGlandsCartilageplateSMCConductionportion－bronchiole&terminalbrochioleSimpleciliatedcolumnar.GobletC（－）Gland（－）Cartilageplate（－）SMCRulesofstructuralvarianceincon

5、ductingportionSmallBrbronchioleTerminalbronchioleEpiPseudostratifiedCiliatedcolumnarSimpleciliatedcolumnarSimplecolumnar**claracellGobletC+++/--Mixedgland+++/--Cartilageplate+++/--SMC++++++Respiratoryportion－RespiratorybronchioleThewallisinterruptedSimplecub

6、oidalEpi,claraCSMCRespiratoryportion－Alveolarduct&alveolarsacThewall,manyalveoliSMC**Simplecuboidal,squamousAlveolarductAlveolarsacNoSMC**Respiratoryportion－alveolus肺泡管SimplealveolarEpi.(1)Respiratoryportion###constituents：respiratorybronchiole，alveolarduct，

7、alveolarsac，alveolus。1.RespiratorybronchioleThewall,fewalveoliopeninto.SimplecuboidalEpi,SMC.(2)Respiratoryportion2.Alveolarduct&alveolarsacThewall,manyalveoliopeninto.KnobsinthewallofalveolarductKnobsissphincter-likeSMC.(3)Respiratoryportion3.alveolus:typeI

8、alveolarCtypeIIalveolarCalveolarseptum.TypeIIalveolarCmacrophageElasticfibertypeIalveolarCTypeIIalveolarCOsmiophilicMultilamellarbodiesblood-airbarrierAlveoliTypeIcellsquamous,coveredmostsurface