急性非静脉曲张性上消化道出血病因及相关因素分析.pdf

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1、806JBengbuMedColl，July2013，Vol．38，No．7［文章编号］1000-2200(2013)07-0806-03·临床医学·老年人急性非静脉曲张性上消化道出血病因及相关因素分析闻静，邵明，孙娟［摘要］目的:探讨老年人急性非静脉曲张性上消化道出血病因及相关因素。方法:对104例经胃镜确诊的老年人急性非静脉曲张性上消化道出血患者(观察组)的临床资料进行回顾性分析，并将104例经胃镜确诊的中青年急性非静脉曲张性上消化道出血患者设为对照组。比较2组患者的病因、失血性周围循环衰竭发生率、住院时间、诱因、合并症、再出血率(住院期间再出血发生率)及病死率。结果

2、:2组患者的病因以消化性溃疡为主，病因构成差异无统计学意义(P＞0．05)。观察组主要诱因为幽门螺杆菌感染及非甾体抗炎药应用，而对照组以幽门螺杆菌感染及饮酒为主。观察组失血性周围循环衰竭发生率、合并症、住院时间、再出血率、病死率均较对照组高(P＜0．05～P＜0．01)。结论:老年人急性非静脉曲张性上消化道出血一旦发生，应尽早明确病因及诱因，合理治疗可降低病死及再出血率。［关键词］上消化道出血;急性非静脉曲张出血;老年人;病因;相关因素［中国图书资料分类法分类号］R573．2［文献标志码］AThepathogenyandrelativefactorsanalysisofa

3、cutenon-varicealuppergastrointestinalhemorrhageinagedpeopleWENJing，SHAOMin，SUNJuan(DepartmentofGastroenterology，TheSecondAffiliatedHospitalofBengbuMedicalCollege，BengbuAnhui233040，China)［Abstract］Objective:Toinvestigatethepathogenyandrelativefactorsofacutenon-varicealuppergastrointestinal

4、hemorrhageinagedpeople．Methods:Theclinicaldataof104agedpeoplewithacutenonvaricealuppergastrointestinalhemorrhagediagnosedbygastroscope(observationgroup)wereretrospectivelyanalyzed，104youngandmiddle-agedpeoplewithacutenonvaricealuppergastrointestinalhemorrhagediagnosedbygastroscopewereseta

5、scontrolgroup．Thecausesofdisease，uncontrolledhemorrhagicincidenceofperipheralcirculatoryfailure，staydays，incentive，complications，therebleedingrate(duringhospitalstay)andmortalityoftwogroupswereanalyzed．Results:Thepepticulcerwasthemaincausesofdiseaseintwogroups，theircausescompositionwasnot

6、statisticalsignificance(P＞0．05)．Helicobacterpylori(Hp)infectionandtheapplicationofnon-steroidalanti-inflammatorydrugwerethemainincentiveinobservationgroup，Hpinfectionanddrinkingwerethemainincentiveincontrolgroup．Uncontrolledhemorrhagicincidenceofperipheralcirculatoryfailure，staydays，compl

7、ications，therebleedingrateandmortalityofobservtiongroupwerehigherthanthoseincontrolgroup(P＜0．05toP＜0．01)．Conclusions:Clearingpathogenyandinducementasearlyaspossibleandtakingreasonabletreatmentduringtheperiodofacutenon-varicealuppergastrointestinalhemorrhagecanreduce