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《DELETION MAPPING OF GENETIC FINE STRUCTURE”遗传“精细结构”地缺失作图: 用算法和启发式方法补充Ad Hoc问题解决方法.pdf》由会员上传分享,免费在线阅读,更多相关内容在教育资源-天天文库。
1、DELETIONMAPPINGOFGENETIC"FINESTRUCTURE”:SUPPLEMENTINGADHOCPROBLEMSOLVINGAPPROACHESWITHALGORITHMSANDHEURISTICSJohnR.Jungck,Dept.ofBiology,BeloitCollege,Beloit,WIandVinceStreif,ComputerCenter,UniversityofWisconsin-EauClair,EauClaire,WIINTRODUCTIONThetransmissionofare
2、alisticanalysisofthehistoryofbiologyisexceedinglyimportantinunderstandingthecontextofdiscoveries,andthepersonal,psychological,sociocultural,andpoliticalmatrixinwhichideasemergeandarepropagated.Biologyeducationtypicallyduplicatesthehistoricallyimportantprocesswhichl
3、edtothediscoveryofthephenomenaunderconsideration.However,asvaluableastheselessonsare,theextensionofhistoricallyemployedmethodsofproblemsolvingmaynotbemostappropriateintheeducationofstudentsincontemporarylaboratorypractice.Weargueherethatitisfrequentlyimportanttore-
4、examinetriedandtruemethodsofscientificproblemsolvingtoseeif(1)moreefficientandrobustprocedurescanbeconstructedorborrowedfromotherfields,and,(2)morepedagogicallysoundprocedurescanbedevelopedwhichprovidegreaterclarityandchanceofachievingsuccessonthepartofstudents.Web
5、elievethat(1)and(2)areintimatelyconnect-ed.Tothisend,I(JRJ)havebeenexamining(forthelast15years)anumberofproblemsolvingtechniqueswidelyusedingenetics1evolution,biochemistryanddevelopmentalbiology(fourcourseswhichIteachfrequently).Theintentisto.helpstudentswithtechni
6、quesandprocesseswhicheachyearasignificantnumberofstudentshaveconsiderabledifficultycomprehendingandusing.Wereporthereacasewhichhasbeennicelysusceptibletoreanalysisandhasbeensuccessfullyusedinclassroomsfornineyears,namelythedeletionmappingofgenes.Aftergoingthroughth
7、etraditionaladhocsolutionwhichistaughtinbasicgeneticstextbooks,wewilldescribetwoalternativeapproachestosolvingsuchproblems.Weassertthatbothalternativeapproacheshaveseveraladvantagescomparedtothetraditionalapproach.RELEVANCEOFNEWMATHTOBIOLOGYMathematicshasnotbeenstr
8、essedinthebiologycurriculum.Theusualreasonsgivenforthisarethatbiologystudentshavedifficultyinstudyingmathematics,fewbiologistshave&broadbackgroun