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时间:2020-05-20
《西酞普兰对冠心病合并焦虑抑郁患者 HAMD SDS评分的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、2512重堕生5年6月第44卷第18期论著·临床研究doi:10.3969/j.issn.1671—8348.ZOI5.18.023西酞普兰对冠心病合并焦虑抑郁患者HAMDSDS评分的影响谢芳,李高飞(北京市中西医结合医院心内科1O0039)[1illlg]目的探讨西酞普兰对冠心病合并焦虑抑郁患者汉密尔顿抑郁量表(HAMD)、抑郁自评量表(sDs)评分、超敏C反应蛋白(hs—CRP)、心率变异(HRV),以及肾素血管紧张素系统(RAS)影响的分析。方法选择2012年1月至2014年8月来该院救治的冠心病合并焦虑抑郁患者160例,按照数字列表法随机平均分为观察组和对照组,其中对照组采,el常规
2、治疗方法,观察组在常规治疗的基础上加用西酞普兰,治疗6周后,比较两组患者的临床疗效、HAMD、SDS评分、hs—CRP、CRP、HRV、RAS情况。结果(1)观察组患者临床总有效率为93.75明显高于对照组的70.00(一10.21,P3、统计学意义(P4、(DepartmentofInternalMedicine—Cardiovascular,BeijingIntergratedChineseandWesternMedicineHospital,Beijing100039,China)[Abstract]ObjectiveToexploretheaffectofcitalopramonHamiltonDepressionScale(HAMD),selfratingDepressionScale(SDS)score,highsensitiveCreactiveprotein(hs-CRP),heartratevariability(HRV),a5、ndreninangiotensinsysterm(RAS)levelsofpatientswithcoronaryheartdiseasecomplicatedwithanxiety-depression.Methods160casesofpatientswithcoronaryheartdiseaseandanxietydepressioninJanuary2012toAugust2014wereselected,theywererandomlydividedintoobservationgroupandcontrolgroupaccordingtothelistofnumbertabl6、emethods,thecontrolgroupof80patientsusedroutinetreatmentmethods,while80patientsinobservationgroupwereaddedwithcitalopramonthebasisofconventionaltherapy,after6weeksoftreatment,theclinicalefficacyandchangesoftheHAMD,SDSscore,score,andhs—CRP,heartratevariability,andreninangiotensinlevelsoftwogroupswer7、ecompared.Results(1)Thetotalclinicaleffectiverateoftheobservationgroupwas93.75,significantlyhigherthan70.0ofthecontrolgroup,thedifferencewasstatisticallysignificant(一10.21,P
3、统计学意义(P4、(DepartmentofInternalMedicine—Cardiovascular,BeijingIntergratedChineseandWesternMedicineHospital,Beijing100039,China)[Abstract]ObjectiveToexploretheaffectofcitalopramonHamiltonDepressionScale(HAMD),selfratingDepressionScale(SDS)score,highsensitiveCreactiveprotein(hs-CRP),heartratevariability(HRV),a5、ndreninangiotensinsysterm(RAS)levelsofpatientswithcoronaryheartdiseasecomplicatedwithanxiety-depression.Methods160casesofpatientswithcoronaryheartdiseaseandanxietydepressioninJanuary2012toAugust2014wereselected,theywererandomlydividedintoobservationgroupandcontrolgroupaccordingtothelistofnumbertabl6、emethods,thecontrolgroupof80patientsusedroutinetreatmentmethods,while80patientsinobservationgroupwereaddedwithcitalopramonthebasisofconventionaltherapy,after6weeksoftreatment,theclinicalefficacyandchangesoftheHAMD,SDSscore,score,andhs—CRP,heartratevariability,andreninangiotensinlevelsoftwogroupswer7、ecompared.Results(1)Thetotalclinicaleffectiverateoftheobservationgroupwas93.75,significantlyhigherthan70.0ofthecontrolgroup,thedifferencewasstatisticallysignificant(一10.21,P
4、(DepartmentofInternalMedicine—Cardiovascular,BeijingIntergratedChineseandWesternMedicineHospital,Beijing100039,China)[Abstract]ObjectiveToexploretheaffectofcitalopramonHamiltonDepressionScale(HAMD),selfratingDepressionScale(SDS)score,highsensitiveCreactiveprotein(hs-CRP),heartratevariability(HRV),a
5、ndreninangiotensinsysterm(RAS)levelsofpatientswithcoronaryheartdiseasecomplicatedwithanxiety-depression.Methods160casesofpatientswithcoronaryheartdiseaseandanxietydepressioninJanuary2012toAugust2014wereselected,theywererandomlydividedintoobservationgroupandcontrolgroupaccordingtothelistofnumbertabl
6、emethods,thecontrolgroupof80patientsusedroutinetreatmentmethods,while80patientsinobservationgroupwereaddedwithcitalopramonthebasisofconventionaltherapy,after6weeksoftreatment,theclinicalefficacyandchangesoftheHAMD,SDSscore,score,andhs—CRP,heartratevariability,andreninangiotensinlevelsoftwogroupswer
7、ecompared.Results(1)Thetotalclinicaleffectiverateoftheobservationgroupwas93.75,significantlyhigherthan70.0ofthecontrolgroup,thedifferencewasstatisticallysignificant(一10.21,P
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