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1、MetastaticBreastcancerCaseReportGeneralinformationName:WUChunHongAge:40ySex:FemaleDateofadmission:February9th,2011Dateofdischarge:April23th,2011ChiefcomplaintShegothypoesthesiaoflowerlimbsandinabilitytowalkformorethanamonthHistoryofpresentillnessThepatientfeltpainonthebackbynoobviousin
2、centivesinJune2010Thepainwastingling,especiallyinnight-timeThepatienttookorallytraditionalChinesemedicine,buthadnottangibleeffectsPast,Personal&FamilyHistoryNohepatitis,hypertension,ordiabetesNosmoking,alcoholordrugabuseNoinheriteddiseasesNohistoryofdrugallergyNormalmenstruationClinica
3、lfindingsTheleftbreastpresentedwithdiffusederythemaandedema,indurationaboutsizeof3.0cm*3.0cmUltrasoundexaminationa3cmleftbreastmassandanormalrightbreastThoracicMRIexaminationThoracicMRIexaminationHigh-densitymasswasshownonthesevenththoracic,andbonedestructionalsohadbeenfound.EnhancedMR
4、ILaboratoryexamination2011-02-091.HepaticfunctionsALT40U/LAST20U/LTBNormal3.TumormarkersCA19-9Normal2.BloodroutinetestHb82g/L RBC4.54×1012/L WBC6.1×109/LPLT201×109/LpuncturebiopsyShereceivedultrasoundguidedbreastcoreneedlepuncturebiopsyPuncturetissuepathology:Theleftbreastinvasiveducta
5、lcarcinomaPrimarydiagnosisBreastcancerwithbonemetastasisTreatmentOnFebruary11,2011inorthopedicdepartment,ThePatientreceived"thesevenththoracictumorresectionandpediclescrewfixation"HistologicalexaminationSevenththoracictumorswasidentifiedasmetastaticcarcinoma,andtheimmunohistochemistryr
6、esultsshowedthepossibilityofbreastcancerbonemetastasiswasverylargeIMMUNOHISTOCHEMICALresultsER++PR++CerbB2-CK20-EMA++,Ckpan+++,CK5/6-TreatmentThepatientrecoveredwell,andthentransferredintoourdepartmentChemotherapytwotimesbeforeoperation:February23,2011March20,2011Thechemotherapyplanwas
7、TECTreatmentAfterthechemotherapyThelesionsareaofleftbreastshowednoreductionTreatmentModifiedradicalmastectomyonmarch31,2011BilateraloophorectomyOnthesamedayHistologicalexaminationTheleftbreastinvasiveductalcarcinomaThebasalresectionmarginoftumorwasclosetothesurroundingnormaltissueThe
