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1、15320110115JournalofClinicalRehabilitativeTissueEngineeringResearchJanuary15,2011Vol.15,No.3/Invitroantibacterialtestofthesurfaceantibacterialcoatingofanewnano-silver/polyurethanebiliarystentHeWei,WangXiang,GaoYing,LiangJun-cai,YuTing-ting,FanZhi-ningAbstractBACKGROUND:B
2、iliarystentshavebeenwidelyusedinavarietyofbenignandmalignantbileductstrictureasapalliativetreatment.Itsshort-termefficacyissignificant,butlong-termuseislimitedbystentrestenosis.OBJECTIVE:Toproduceanewantibacterialcoatingusedinbiliarystentbymeansofnano-silver/polyurethane
3、,andtotestinvitroantibacterialproperties.METHODS:Firstly,compositematerialsweremadeofnano-silverandpolyurethanebyinsitureductionmethod.AntibacterialtestwasusedtodetectinvitroantibacterialpropertiesagainstStaphylococcusaureus,Escherichiacoli,Pseudomonasaeruginosa,Klebsiel
4、lapneumoniaeandEnterococciofthreegroups:experimentalgroup(nano-silver/polyurethane),positivecontrolgroup(filterpapersoakedinsilvernitratesolution)andnegativecontrolgroup(polyurethane),antibacterialzonediametersweremeasuredandanalyzed.RESULTSANDCONCLUSION:Thedifferencewas
5、notsignificantbetweenexperimentalgroupandpositivecontrolgroupintheantibacterialeffectonStaphylococcusaureus,Escherichiacoli,Pseudomonasaeruginosa,KlebsiellapneumoniaeandEnterococci.Nano-silver/polyurethanecompositehasgoodantibacterialpropertyandbetterstability.HeW,WangX,
6、GaoY,LiangJC,YuTT,FanZN.Invitroantibacterialtestofthesurfaceantibacterialcoatingofanewnano-silver/polyurethanebiliarystent.ZhongguoZuzhiGongchengYanjiuyuLinchuangKangfu.2011;15(3):453-456.[http://www.crter.cnhttp://en.zglckf.com]InstituteofDigestiveEndoscopyandMedicalCen
7、terforDigestiveDiseases,SecondAffiliatedHospitalofNanjingMedicalUniversity,Nanjing210011,JiangsuProvince,ChinaHeWei,Studyingformaster’sdegree,InstituteofDigestiveEndoscopyandMedicalCenterforDigestiveDiseases,SecondAffiliatedHospitalofNanjingMedicalUniversity,Nanjing21001
8、1,JiangsuProvince,Chinabingbing_he@yeah.net//(/)()()3//doi:10.3969/j.issn.1673-8225.2011.03.018Correspo
