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ID:33090185
大小:5.86 MB
页数:55页
时间:2019-02-20
《康复训练对脑梗死大鼠梗死区神经细胞糖代谢的影响》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、万方数据reportislimited,andfailedtofullyclarifythetherapeuticmechanismofexercisetrainingonischemicCI.ThisexperimenthasestablishedtheischemicCImodelofrat,givingtheminterventionofexercisetraining,andobservingthechangeofglucosemetabolismindexoftheinfarctionar
2、eaanditsnervousbehaviorbeforeandafterinterventionthroughmethodsofexercisetest,balancebeamtest,screentest,microPET,18F-FDGandSUVtoverifythetreatmenteffectofexercisetrainingonischemicCIandexploreitspossiblemechanismonmotornerveinrecoveryofischemicCI.Meth
3、ods:1.Objectsandinterventions:throughtherandomnumbertablemethod,28SDratsthatfromtheanimallaboratorycenterofSichuanmedicaluniversitywererandomlydividedintofourgroups,whicharetheshameoperationgroup,themodelgroup,therehabilitationgroupandthedruggrouprespe
4、ctively(n=7).TheMCAOmodelwasmadebasedonthemethodofsuture—occludedfortheratsfromthemodelgroup,therehabilitationgroupandthedruggroup.AndonlyneckvascularexposureprocessingWasdonefortheshameoperationgroup.Afterthefailureofratsmoldingandflakeoff,covergroupw
5、ascarriedoutbyrandomprincipleduringtheexperimenttoguaranteethenumberofratsofallgroups.Theshameoperationandmodelgroupwereraisednormally;rehabilitationgroupwasgiventhetrainingofbalancebeam,rotatingstickandrollertotraintheabilitiesofgrasping,balancing,wal
6、kingandrotatingofrats;andEdaravoneintraperitonealinjectiontreatmentwasgiventothedruggroup.2.Observationindex:①Testevaluationofexercise,screenandthebalance5万方数据beamwerecarriedoutwithfourgroupsofratsinld,7d,14d,21dand28dfivetimerespectively,observingthem
7、ovementandneuralfunctionchangesofrats.②UsingmicroPET/CTdetectSUVvaluesofFDGoffourgroupsratsinldand28dtimes,observingthesugarmetabolismchangesofbrainnervecellsindifferentinterventioncases.3.Statisticalprocessing:Usingstatisticalsoftware(SPSS17.0)todosta
8、tisticalanalysisfordata,allthedatawereexpressedbyz-I-s,andthedatawasconfirmedobeyingthenormaldistribution.Teststandardis0【=O.05,beforeandafterthecomparisionofthetreatmentinthegroup,pairedttestCanbeused,andone-wayanalysisofvarianceCanbeu
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