康复训练对脑梗死大鼠梗死区神经细胞糖代谢的影响

康复训练对脑梗死大鼠梗死区神经细胞糖代谢的影响

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页数:55页

时间:2019-02-20

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1、万方数据reportislimited,andfailedtofullyclarifythetherapeuticmechanismofexercisetrainingonischemicCI.ThisexperimenthasestablishedtheischemicCImodelofrat,givingtheminterventionofexercisetraining,andobservingthechangeofglucosemetabolismindexoftheinfarctionar

2、eaanditsnervousbehaviorbeforeandafterinterventionthroughmethodsofexercisetest,balancebeamtest,screentest,microPET,18F-FDGandSUVtoverifythetreatmenteffectofexercisetrainingonischemicCIandexploreitspossiblemechanismonmotornerveinrecoveryofischemicCI.Meth

3、ods:1.Objectsandinterventions:throughtherandomnumbertablemethod,28SDratsthatfromtheanimallaboratorycenterofSichuanmedicaluniversitywererandomlydividedintofourgroups,whicharetheshameoperationgroup,themodelgroup,therehabilitationgroupandthedruggrouprespe

4、ctively(n=7).TheMCAOmodelwasmadebasedonthemethodofsuture—occludedfortheratsfromthemodelgroup,therehabilitationgroupandthedruggroup.AndonlyneckvascularexposureprocessingWasdonefortheshameoperationgroup.Afterthefailureofratsmoldingandflakeoff,covergroupw

5、ascarriedoutbyrandomprincipleduringtheexperimenttoguaranteethenumberofratsofallgroups.Theshameoperationandmodelgroupwereraisednormally;rehabilitationgroupwasgiventhetrainingofbalancebeam,rotatingstickandrollertotraintheabilitiesofgrasping,balancing,wal

6、kingandrotatingofrats;andEdaravoneintraperitonealinjectiontreatmentwasgiventothedruggroup.2.Observationindex:①Testevaluationofexercise,screenandthebalance5万方数据beamwerecarriedoutwithfourgroupsofratsinld,7d,14d,21dand28dfivetimerespectively,observingthem

7、ovementandneuralfunctionchangesofrats.②UsingmicroPET/CTdetectSUVvaluesofFDGoffourgroupsratsinldand28dtimes,observingthesugarmetabolismchangesofbrainnervecellsindifferentinterventioncases.3.Statisticalprocessing:Usingstatisticalsoftware(SPSS17.0)todosta

8、tisticalanalysisfordata,allthedatawereexpressedbyz-I-s,andthedatawasconfirmedobeyingthenormaldistribution.Teststandardis0【=O.05,beforeandafterthecomparisionofthetreatmentinthegroup,pairedttestCanbeused,andone-wayanalysisofvarianceCanbeu

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