癫痫患者认知功能的变化与其影响因素的分析

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1、MaterialandMethods：119patientsgotstandardizedprocedureofdiagnosisandtrcatmentandandwel"eadministeredthesamebatteryofcomprehensiveneuropsychologicaltestsatbaselineandafter2to3years．AbatteryofneuropsychologicaltestscomprisesAuditoryVerbalLearningtest,LogicalMemorytest，DigitalSymboltest,Blockdesign,

2、Strooptest，TrailMakingtest,VerbalFluencytest,Rey-OsterriethComplexFiguretest,BostonNamingtestandDigitalSpantest．Results：田kpatientsshowedsignificantimpairmentinimmediateanddelayrecallofLogicalMemorytestandimprovementinimmediateanddelayrecall，cuedrecall,recognitiontaskandsemanticclusteringofAuditor

3、yVerbalLearningtest,DigitalSymboltest,correctofStrooptestBandC，VerbalFluencytestpart2，BostonNamingtestandDigitalSpantestafter2-3years．砌etheothercognitivedomaindidnotexhibitanyimportantchange，thoughthetimeofTr碰Makingtestprolonged．Wefoundthechangesofcognitivefunctionwererelatedtothedurationofepilep

4、sy,theageatOBSCt，seizureseverity,accountofantiepilepticdrugs，ahistoryofsimplepartialseizure，ageandeducationlevel．111edurationofepilepsyisrelatedtothechangesofcuedrecallofAuditoryVerbalMemorytest，thecorrectofStrooptestC，SIE，VerbalFluencytestpart2．andT珊MakingtestA．AhistoryofSimplepartialseizureisre

5、latedtothechangesofsemanticclustering3ofAuditoryVerbalMemorytest，thecorrectofStrooptestAandimmediaterecallofLogicalMemorytest．田硷accountofantiepilepticdrugsisrelatedtothechangesofcuedrecallandsubjectiveorganizationofAuditoryVerbalMemorytestandDigitalSymboltest．111eageatonsetisrelatedtothechangeofs

6、emanticclustering3ofAuditoryVerbalMemorytest．11圮seizureseverityisrelatedtothechangeofDigitalSymboltest．田kageisrelatedtothechangesofdelayrecallofAuditoryVerbalMemorytest,immediaterecallofLogicalMemorytest,DigitalSymboltestandDigitalSpantest-啊硷educationlevelisrelated3复旦大学硕士研究生学位论文tothechangesofsema

7、nticclusteringandsubjectiveorganizationofAuditory、，砷alMemorytestandimmediateanddelayrecallofLogicalMemorytest．Conclusion：Althoughthepatientshavegeneralcognitivedeficits，theimpairmentisnotgraduation．Thecognitivefunction