欢迎来到天天文库
浏览记录
ID:34618028
大小:790.74 KB
页数:6页
时间:2019-03-08
《4类材料包裹治疗犬梭形动脉瘤的高频超声观察与病理学评价》由会员上传分享,免费在线阅读,更多相关内容在教育资源-天天文库。
1、福建医药杂志2011年1O月第33卷第5期FujianMedJ,October20l1,Vo1.33,No.5·l··论著·4类材料包裹治疗犬梭形动脉瘤的高频超声观察与病理学评价福建医科大学省立临床医学院福建省立医院(福州350001)张文清漆松涛沈衍富黄绳跃袁苏涛魏晨斌俞训彬丁桂升黄绍嵩林伟魏德【摘要】目的探讨生物膜等4类材料包裹治疗犬梭形动脉瘤(FFA)模型的远期疗效。方法1O只犬的2O枚梭形动脉瘤分别用生物膜、自体颈外静脉(EJV)、膨体聚四氟乙烯膜片(e-PTFE)、涤纶片等建立完全匹配包裹模型各5枚,观察建模后血流动力学变化与病理学改变。结果随建模时间延长,EJ
2、V降解、模型膨胀性增大,瘤壁机化、钙化、炎症反应严重,24个月破裂并闭塞1枚;涤纶片无降解、瘤壁炎症反应严重,6个月5枚瘤腔完全闭塞;~PTFE无降解、瘤壁炎症反应轻、有钙化趋向,24个月~PTFE出现1枚闭塞;生物膜包裹3个月后开始多层次降解,并诱导组织再生,无炎症反应。高频超声动态观察提示不同包裹材料与瘤壁微小间隙、增生斑块、血管弹性等的演变过程以及模型的不同部位血流速度有着不同的变化(P3、疗的理想材料。【关键词】动脉瘤模型;包裹材料;高频超声;生物力学性能;炎症反应【中图分类号1R730.21;R730.41;R732.21【文献标识码】A【文章编号】1002—2600(2011)05~0001-05Caninefusiformaneurysmmodelwithwrappingoffourkindsgraft:evaluatedhistomorphologyandwithhigh’frequencyuItrason0graphyZHANGWen—qing,QISong—tao,SHENYah一,HUANGSheng—yue,YUANSu—tao,WEICh4、en-bin,yUXun~bin,DINGGui—sheng,HUlANGShao—song,LINWei,WEIDe.Fianprovincialhospital,ProvincialClinicalMedicalcollegeofFujianmedicaluniversity,Fuzhou350001,China[Abstract]0bjectiveToexaminethehemodynamicschangesandthepathologicalfeaturesonthecaninefusiformaneu—rysm(FFA)modelsafterbeingwrapp5、edbybiologicalgrafandsoon,andtoevaluatethelong-termeffectoffourkindsgraftinwrappingofcerebralaneurysms.MethodsTwentyFFAcaninemodelswerereproducedin10experimentaldogswererandomlydividedintoA(biologicalgraf),B(autogenousexternaljugularvein,EJV),C(expandedp。lytetrafluor0ethylene,~PTFE),D(Dac6、ronfilm)fourgroups,fiveforeachgroup,usingperfectmatchstatemethodwerewrappedforthetreatment.Highfre—quencyultrasoundwascarriedoutin1,3,6,12and24monthsandpathologicalfeatureswereevaluatedin24monthsaftersurgicalprocedure.ResultsAlongwiththeprolongationoftime.EJVcompletelydegradedandabsorbed,7、themodelsgrewin8nexpansilewayandtheaneurysmswallill—defined,inflammatorycellinfiltration,calcification,andorganization.Buttherewasonecasespontaneousrupturedandoccludedat24monthsfollowingsurgery.TheaneurysmalcavitieswereoccludedafterDacronwrappinginfivecasesatsixmont
3、疗的理想材料。【关键词】动脉瘤模型;包裹材料;高频超声;生物力学性能;炎症反应【中图分类号1R730.21;R730.41;R732.21【文献标识码】A【文章编号】1002—2600(2011)05~0001-05Caninefusiformaneurysmmodelwithwrappingoffourkindsgraft:evaluatedhistomorphologyandwithhigh’frequencyuItrason0graphyZHANGWen—qing,QISong—tao,SHENYah一,HUANGSheng—yue,YUANSu—tao,WEICh
4、en-bin,yUXun~bin,DINGGui—sheng,HUlANGShao—song,LINWei,WEIDe.Fianprovincialhospital,ProvincialClinicalMedicalcollegeofFujianmedicaluniversity,Fuzhou350001,China[Abstract]0bjectiveToexaminethehemodynamicschangesandthepathologicalfeaturesonthecaninefusiformaneu—rysm(FFA)modelsafterbeingwrapp
5、edbybiologicalgrafandsoon,andtoevaluatethelong-termeffectoffourkindsgraftinwrappingofcerebralaneurysms.MethodsTwentyFFAcaninemodelswerereproducedin10experimentaldogswererandomlydividedintoA(biologicalgraf),B(autogenousexternaljugularvein,EJV),C(expandedp。lytetrafluor0ethylene,~PTFE),D(Dac
6、ronfilm)fourgroups,fiveforeachgroup,usingperfectmatchstatemethodwerewrappedforthetreatment.Highfre—quencyultrasoundwascarriedoutin1,3,6,12and24monthsandpathologicalfeatureswereevaluatedin24monthsaftersurgicalprocedure.ResultsAlongwiththeprolongationoftime.EJVcompletelydegradedandabsorbed,
7、themodelsgrewin8nexpansilewayandtheaneurysmswallill—defined,inflammatorycellinfiltration,calcification,andorganization.Buttherewasonecasespontaneousrupturedandoccludedat24monthsfollowingsurgery.TheaneurysmalcavitieswereoccludedafterDacronwrappinginfivecasesatsixmont
此文档下载收益归作者所有