! Joshi et al.(2011)-Media coverage of off-label promotion.pdf

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1、Availableonlineatwww.sciencedirect.comResearchinSocialandAdministrativePharmacy7(2011)257–271OriginalResearchMediacoverageofoff-labelpromotion:AcontentanalysisofUSnewspapersAvaniD.Joshi,B.Pharm.,DipenA.Patel,B.Pharm.,DavidA.Holdford,R.Ph.,M.S.,Ph.D.,F.A.Ph.A.*VirginiaCommonw

2、ealthUniversity,SchoolofPharmacy,McGuireHall,Room213,POBox980533,1112EastClaySt,Richmond,VA23298-0533,USAAbstractBackground:Promotionofdrugsforoff-labeluseisnewsworthy,becauseitisanillegalbutalltoocommonstrategyusedbypharmaceuticalcompanies.Theprintmediaareanimportantsourceo

3、finformationaboutcoverageofoff-labelpromotionofdrugsanddevicesandcaninfluencepublicperceptionsofthepractice.Objectives:Printmediacoverageofoff-labelpromotionduringtheyears1990-2008weredescribedandquantified.Theprimarythemesandgeneraltonesrelatingtooff-labelpromotionarticlesweree

4、valuated.Generalconcernsassociatedwithoff-labelpromotionandcomplaintsaboutspecificbrandnamedrugswerealsoidentified.Methods:Contentanalysesofthetop6USnewspaperswereconductedovertheperiodof1990-2008toanalyzethemediacoveragegiventooff-labelpromotionofdrugsanddevices.Headlinesandfu

5、lltextofarticleswereanalyzedforprimarythemesandtonesofthecoverage.Intercoderreliabilitytestswereperformedonallthestudyvariables.Results:Onehundredandonearticleswereidentifiedmeetingthestudyinclusioncriteria.Coveragevariedbynewspaper.TheWallStreetJournalhadthemostcoverageonth

6、etopic(45%),andUSATodayandChicagoTribunehadtheleastcoverage(5%).Overall,mostofthestoriessampledweredeemedtohaveanegativetoneincoverage(77%),focusingmainlyonlawsuitsagainstdrugcompaniesforpromotingtheirÒdrugsforoff-labeluses.Pfizer’sNeurontin(PfizerInc.,NewYork,NY10017,USA)andJ

7、ohnson&ÒJohnson’sRetin-A(Orthoneutrogena,LosAngeles,CA90045,USA)receivedthemostmediaattention.Conclusion:Thenewsmediahelpsshapepublicunderstandingofpromotionalpracticesofpharmaceuticalcompaniesandtheirpotentialbenefitsandharms.Thisstudysuggeststhatprintmediacoverageisgeneral

8、lynegativeaboutoff-labelpromotion,focusingonlegalactionstakenagainstdrugcompaniesan