益肾健脾活血化痰法稳定冠状动脉粥样硬化斑块的临床研究

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1、山东中医药大学硕士学位论文益肾健脾活血化痰法稳定冠状动脉粥样硬化斑块的临床研究姓名：董晓斌申请学位级别：硕士专业：中医内科学指导教师：包培荣2003.4.20提要、ibil91目的观察中药组方对冠状动脉粥样硬化(CAS)斑块的稳定作用并探讨其作用机制。方法70例冠心病心绞痛患者随机分成两组，治疗组36例，对照组34例。治疗组给予益肾健脾活血化痰之中药煎剂和常规西药治疗，对照组给予辛伐他汀和常规西药治疗，观察治疗前后临床症状和化验室检查指标的变化。结果经治疗四周后，治疗组症状改善总有效率为97，22％，显效率为72．22％，

2、与对照组比较有显著性差异(P

3、tingthekidneyandfortifingthespleenandquickeningthebloodandtransformingthephlegmSpecialty：InternalMedicineofTraditionalChineseMedicineAuthor：DongXiaobinTutor：BaoPeirongAbstractobjeetive：Toobservethestabilizationeffectofchinesemedicineprescriptiontocoronaryatheroscl

4、erosisplaqueandexploreitsmechanismofeffect．Methods：Seventypatientsofcoronaryheartdisease(CHD)withanginaweredividedrandomlyintotreatmentgroup(36cases)andcontrolgroup(34cases)．Conventionalwesternmedicaltherapywasgiventobothgroups．Atthesametime，thetreatmentgroupreciv

5、edthedecoctiontoboostthekidneyandfortifythespleenandtoquickenthebloodandtransformthephlegmAndthecontrolgrouprecivedSimvastatin．Thechangesofclinicalsymptomsandlaboratoryindexsinallthepatientswereobservedbeforeandaftertreatment．Results：Inthetreatmentgroup，thetotalef

6、fectiverateofmelioratingsymptomsandtheremarkableratewererespectively97．22％and72．22％，whichweresignificantlybetterthanthoseofthecorttrolgroup，P

7、remarkablyaftertreatment，whichwerestatisticallydifferentcomparedwiththoseofthecontr01group．P<0．05orP<0．01．Conclusion：TheChinesemedicinewiththetherapeuticmethodofboostingthekidneyandfortifingthespleenandquickeningthebloodandtransformingthephlegmhastheevidenteffectt

8、ostabilizethecoronaryatherosclerosisplaque．Keywordsthecoronaryatherosclerosisplaque；boostingthekidneyandfortifingthespleenandquickeningthebloodandtransf