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1、JournalofMedicalVirologyCervicalHumanPapillomavirusInfectioninChineseWomenForPeerReviewJournal:JournalofMedicalVirologyManuscriptID:JMV-11-2494Wiley-Manuscripttype:ResearchArticleDateSubmittedbythe12-May-2011Author:CompleteListofAuthors:wang,yumin;TheFirstAffiliatedHospitalo
2、fWenzhouMedicalCollege,DepartmentofLaboratoryMedicinechen,Jie;TheFirstAffiliatedHospitalofWenzhouMedicalCollege,TheIntensiveUnit,Tao,Zhihua;TheFirstAffiliatedHospitalofWenzhouMedicalCollege,DepartmentofLaboratoryMedicineHong,Wangdong;TheFirstAffiliatedHospitalofWenzhouMedica
3、lCollege,DepartmentofDigestionMedicineKeywords:Humanpapillomavirus,Chinesewomen,CervicalcanceJohnWiley&SonsPage1of14JournalofMedicalVirology1234CervicalHumanPapillomavirusInfectioninChineseWomen5611*213YuminWang,JieChen,ZhihuaTao,WangdongHong7819DepartmentofLaboratoryMedicin
4、e,TheFirstAffiliatedHospitalofWenzhouMedicalCollege,10Wenzhou325000,China211TheIntensiveUnit,TheFirstAffiliatedHospitalofWenzhouMedicalCollege,Wenzhou12325000,China313DepartmentofDigestionMedicine,TheFirstAffiliatedHospitalofWenzhouMedicalCollege,14Wenzhou325000,China1516Abs
5、tract1718Humanpapillomavirus(HPV)havebeenrecognizedasoncogenicfactorincervicalForPeerReview19carcinoma.TherewasanincreasedincidenceofcervicalcancerinChinesewomen.2021However,littleisknownabouttheprevalenceofHPVgenotypesinChinesewomen22withcervicalcancerandriskfactorsofcervic
6、alcancer.Cervicalexfoliatedcellswere2324prospectivelycollectedfrom792womenwithcervicalcancerreferredforcolposcopic25examination.TheindividualHPVgenotypesinthesespecimenswereidentified(HPV2627GenoArraytestkit;HybribioLtd.,HongKong).Meanwhile,theclinicaldataand2829laboratoryre
7、sultofthesepatientsweregathered.HPV-positivewasfoundin588/79230(74.2%).TheprevalenceoftheHR-HPVwere516/792(65.2%).and51.0%ofthese3132patientswereinfectedwithmixturesofHRgenotypes.HPVpositiverateinvarious33clinicalstagesanddifferentiationdegreeofuterinecervicalcancerhadnostat
8、istical3435differences(P>0.05).HPVpositiverateinSqua-mouscancerandadenocarc
