The Japanese Breast Cancer Society Clinical Practice Guideline for systemic treatment of breast cancer, 2015 edition

The Japanese Breast Cancer Society Clinical Practice Guideline for systemic treatment of breast cancer, 2015 edition

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页数:14页

时间:2019-07-11

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1、BreastCancerDOI10.1007/s12282-016-0670-ySPECIALFEATUREJapaneseBreastCancerSocietyGuidelines2015TheJapaneseBreastCancerSocietyClinicalPracticeGuidelineforsystemictreatmentofbreastcancer,2015edition1234TomohikoAihara•TatsuyaToyama•MasatoTakahashi•YutakaYamamoto•5678FumikataHa

2、ra•HiromitsuAkabane•TomomiFujisawa•TakashiIshikawa•9101112ShigenoriNagai•RikiyaNakamura•JunjiTsurutani•YoshinoriIto•13HirofumiMukaiReceived:26November2015/Accepted:18December2015ÓTheJapaneseBreastCancerSociety2016IntroductionRH)agonistinpremenopausalprimarybreastcancerpatie

3、ntswaschangedtogradeC1;CQ11,therecommen-HerewepresenttheEnglishversionofTheJapanesedationforadjuvantuseofanthracyclineandtaxaneinBreastCancerSocietyClinicalPracticeGuidelinesfornode-positiveprimarybreastcancerpatientswasdown-systemictreatmentofbreastcancer,2015edition.which

4、gradedfromAtoB;CQ37,therecommendationforwasrevisedinJuly,2015.Differencesfromthemostrecentmultigenesignaturesaspredictivefactorsfortheefficacypreviousversionincludethefollowingnewlyaddedclini-ofadjuvantchemotherapyusingOncotypeDXwasup-calquestions:CQ19,CQ21,CQ26andCQ35.grade

5、dtoB,whileothergenetictestsremainedasC1.RecommendationgradeswerechangedaccordingtoOtherchanges:CQ39,theregimenwasstratifiednewlyreportedevidenceoronreconsiderationoftheaccordingtotheriskofchemotherapy-inducednauseaandexistingdataasfollows:CQ4andCQ8,recommendationvomiting;CQ4

6、0,preventiveuseofgranulocyte-colonyfortamoxifenadministrationfor10years;CQ5,therec-stimulatingfactor(G-CSF)forfebrileneutropeniawasommendationforadjuvantuseofexemestaneincombi-added,forwhichtherecommendationisgradeA.nationwithaluteinizinghormone-releasinghormone(LH-Thisarti

7、cleisanEnglishdigestoftheClinicalPracticeGuidelineofBreastCancer2015,publishedbyKanehara&Co.,Ltd.Detailsofrecommendationgradeswereexplainedinthepreviousreport(BreastCancer.2015;22:14).7&TomohikoAiharaDepartmentofBreastOncology,GunmaPrefecturalCanceraiharat@aiharabreast.comC

8、enter,Ota,Japan81DepartmentofBreastSurgery,TokyoMedicalUniversityBreastCenter,Aiha

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