中国2型糖尿病防治指南（2020年版）

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59(2)⚜Ëফ3Ø%জ⚜Ëᒹº⚜Ë⚜Ë'(ᱥ஺᪷`ὅḄ⊈åæJ⌱Èéøù2ëḄÞßᫀ஺ÍHbAlc:úr4JÆᵨéø2ëḄÞßᫀ஺ঝéø1ë⚜Ë]WXḄᑺ¯àü-0.2Ukg-'•’⚶஺᪷ὅῳ⊈᦮ᵨ35ᜩ᦮1$᪷⊈$᦮%4U()ῳ⊈*᪗஺ঞ-2$⚜0123Ḅᑺ6780.2~0.4U-kg-'k'ᢥ111Ḅ@AᑖCᑮE⚶F⚶஺᪷ῳ⊈F⚶⊈ᑖG᦮⚶FE⚶Ḅᵨ35ᜩ᦮1$᪷⊈$᦮Ḅᑺ804U,(ᑮ⊈*᪗஺টT1DMᙠNᨴP▤RSTPUᵨ⚜0-2~3$஺⚜0VWᵨXT1DMḄYP⊈Zᑴ஺(3)^ῳ_`ᱥ1bcdḄ^_`ᱥeᨵghij^(IDegAsp),pq67r0.1~0.2U•kg-1,d''t3Xu⚶᪷ῳ⊈᦮ᑺ()*᪗஺vwᡈHbAlc>8.0%ḄὅS⌱ᑺ23஺ghij^ᜩ1$ᶭᑺ*ᑮ0.5U•kg-1•d-1ᡈ30~40U⚶⊈ZᑴVᡈὅᜩᨵ$u⚶Sὃ⇋ᦋ8ᜩ2$ফ஺()Ḅ$Fᢝ(CSII)[227-232]1.$1ᙠ23ᶭḄẠcᐙᑖḄᑺ᦮᝞ὅḄ⊈¢*᪗ᡈ£¤¥¦Ḅ§⊈◤©6ª

60«ᓄᶭᫀ஺S¯°ᵨ⚶+Ạ²2~4$/d´ᡈ-2~3$⚜0_`ᱥ©µ¶ᓄᶭ஺Uᵨ·᝞1²1´⚶+Ạ1᪷¸⚶ஹ⚶Fṑ⊈ᑖG᦮⚶Ḅᵨ᪷ῳ⊈᦮ṑẠᵨ,3~5ᜩ᦮1$᪷⊈$᦮Ḅᑺ8»4U,()⊈*᪗஺t3Uᵨ⚶+ẠᫀSᙠẠḄẠc°ᵨ¼ᙠ6⚶²᝞u⚶´½ᵨ⚶Ḅᫀ஺¾᪷⊈ḄZᑴ¿ÀÁÂÃᔲᙠᐸÆ⚶½ᵨ⚶஺²2´-2~3$⚜0²⚜0Ç-2$⚜0_`ᱥ-2~3$´1᪷ṑF⚶⊈©µᑺ᦮35ᜩ᦮1$(ᑮ⊈*᪗஺ẆÉÊËᙠT2DMὅ°ᵨ⚶+Ạ²4$/d´ᡈ-3$⚜0_`ᱥ©µᶭÌὅᙠHbAlcÍÎஹ§⊈ÏÐ᳛ஹÒᑺFÓÔÕḄÖ×☢ÙÚÊÛGফ஺2.CSII1ÜÝÞᓝÌà஺²á´TP¶ᓄᶭফ3-23âT1DMὅ67◤⌕$ᡈCSII,ᓽ◤⌕YPḄ¶ᓄᶭ஺ÓXHbAlcå9.0%ᡈῳ⊈211.1mmol/LêÚÊ⊈ëìḄíîïT2DMὅSðñTP¶ᓄᶭᶭòᙠ2ᕜ)3ôᨴ8Wᶭb᪗8ῳ⊈4.4~7.0mmol/L,õῳ⊈GO.Ommol/L,SᨚV¯HbAlc*᪗ù8ᶭb᪗஺

61TP¶ᓄᶭᫀS¯°ᵨ$ஹ-23$⚜0ᡈCSH஺᝞ú°ᵨḄÃ$ᫀ⊈ûüᫀ◤ᕜ)ý3d,ᜩ34ôòþ஺᪷¸⚶ஹ⚶Fṑ⊈ᑖG᦮Eஹ¸ஹ⚶Ḅᵨ᪷ῳ⊈᦮ṑẠᵨ35ᜩ᦮1$$᦮Ḅᑺ8%4U,(ᑮ⊈*᪗஺᝞ú°ᵨḄÃ-23$⚜0⊈ûüᫀ◤ᕜ)ý3d,ᜩ34ôòþ஺᪷ṑF⚶⊈©µᑺ᦮35ᜩ᦮1$᪷⊈$᦮Ḅᑺ804U,(ᑮ⊈*᪗஺᝞ú°ᵨḄÃCSH,⊈ûüᫀ◤ᕜ)ý3d,ᜩ5~7ôþ஺᪷⊈᦮ᑺ()⊈*᪗஺¶ᓄᶭÿ
ὅ⃩ᶭὅḄᦟ஺ᓄᶭ"#$%&'Ḅὅ(ᔲ*+,ᵨᶭᡈᦋᵨᐸ12ᱥᶭ4ᵫ678᪷:ὅḄᐹ<=>ᩭ@A஺ᶭB᪗DEF&'ὅGHὃ⇋AK᝞3MᨴOPQRSTU⊈WXᓣZᓽ\ῳ⊈27.0mmol/Lᡈ⚶_2h⊈210.0mmol/LḄὅ`abc2ᱥᶭ஺KdOᱯf=>gḄ4ᵨhijஹlmஹno
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62©;:HbAk=ᓄ⊈@ABTFPG=Cῳ⊈E42ὅḄᶭuv஺ᐸA2ᶭ3Mᨴ_HbAlc27.0%Ḅ2ὅᶭuvBa2ὅHbAlc^9.0%ᡈFPG^ll.1mmol/LḄᶭuvஹF6᪵H-1IJKLᑺ

63GLP-1RAGLP-1=ஹ?<@AB>=CᜩᯠGLP-1F஺GLP-1RAJᨵᦔMN⊈@-PQᑖឮTUVBXYZP-MN\]-ᦋᗐ⊈ᾦabMN⊈c஺GLP-1RAJᓫefᵨᡈᐸjM@kᱥὶᔠfᵨ஺ᒹopqT2DMvὅḄ⚗yzẆ|ᙳ~-GLP-1RAPᨵᦔᦋᗐῳb⚶2h⊈@-MNHbAlc,MN\]஺M@kᵬBᡈFᶭᜫᦔ-6ᵨGLP-1RAJᦋᗐ⊈@஺ὶᔠBᡈFᵬ᠚ᑺJMNHbAlcC0.8¡\]¢M1.1kgব¦஺ᵬ§BᡈF¨ᑴª«ḄT2DMvὅ6ᵨᑭ20ug/d,24ᕜ+᠚ᑺῳ⊈@¢M0.48mmol/L,⚶2h⊈@¢M4.28mmol/L,HbAlcMN0.36%ফ21஺⊈@¨ᑴª«ḄT2DMvὅµ¶?<@

641.5mg/ᕜᡈ0.75mg/ᕜᓫkᶭ26ᕜ-+¹ᑡº᱐ᓫkᑖ¼MNHbAlcC0.58%0.32%ফ½஺ᙠᵬ§BᡈF¿¨ᑴª«ḄT2DMvὅpµ¶?<@1.5mg/ᕜᡈ0.75mg/ᕜᶭ26ᕜ,HbAlcᑖ¼MN1.73%1.33%\]Àᓄᑖ¼CT.47kg-0.88kg[244]oÄÅÆẆ|ÇÈ->=ᶭ3Éᨴ+$Ë\]¢M10.05kg,ῳ⊈@¢M3.05mmol/L,⚶2h⊈@¢M5.46mmol/L,HbAlcMN2.87%Ì451°ᵬ…iὶᔠ100Pg/ᕜஹ200pg/ᕜᶭ24ᕜ,ᑖ¼+᠚ᑺMNHbAlcÐ1.51%1.49%ÒḄ°ᑭ<=18mg/d+Ó¹ᑡÔ100mg/dMNHbAlc0.67%,\]¢M2.09kg[247]GLP7RAὶᔠUVÕᶭoPÖ1UVÕᑺ×஺ᑭ<=ὶᔠUVÕJfUVÕᑺ×Ö166%,\]+$ËMN5.62kg[248]oᒹoᐰᳫ56004ÚvὅḄ7⚗ᜧÜyzẆ|Ý⃓ᑖ᪆ÇÈ-GLP-1RAMN3P-MACEBá⊈âãäᡈåæãឋáç᫱ãᡈåæãឋᓨpTᔠêëF12%,MNá⊈âãäì◅12%,Ö1æãឋåæãឋᓨp16%,Ö1æãឋᡈåæãឋáç᫱ã9%,MNᐰîãäì◅12%,Ö1îáï⊦ñò▾9%,Ö1ôTᔠõöB÷øᜧ×ùúûஹôüᳫý0᳛¢M30%ஹÿ
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