顺德地区eb病毒感染现状及影响因素分析

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1、顺德地区EB病毒感染现状及影响因素分析田娜娜潘建南周成宇罗美华吕伟标麦如蓝SP艳晖刘丽于新发广东药科大学公共卫生学院南方医科大学顺德医院目的了解顺德地区人群中EB病毒的流行状况及EB病毒感染的影响因素。方法于2015年46月对顺德地区大良、陈村、杏坛三个镇17727名居民进行问卷调查，采用酶联免疫吸附法检测EB病毒核心抗体TgA(NAl-TgA)、EB病毒衣壳抗体IgA(VCA-IgA)水平。采用非条件Logistic回归探讨EB病毒感染的影响因素。结果共计纳入17581人。EB病毒NAl-IgA、VCA-IgA阳性率分别为3.23%和6.76%。EB病毒感染

2、率为9.49%。男性的EB病毒感染风险高于女性，0R值为1.15(95%CI=1.04l.28);与〈40岁年龄组比较，4049岁年龄组感染风险降低(0R=0.86;95%CT=0.731.01),而50岁以后随年龄增长,感染风险增加;与小学及以下文化程度者相比，文化程度高者感染风险降低;吸烟者与非吸烟者相比，其感染风险增高(0R=l.19;95%CI=1.01l.39)。结论顺德地区男性EB病毒感染风险高于女性，年龄与EB病毒感染风险呈“V”型关系，高文化程度是EB病毒感染的保护因素，吸烟可能是EB病毒感染的危险因素。关键词：EB病毒;EB病毒核心抗体IgA

3、;EB病毒衣克抗体IgA;危险因素;AnalysisontheinfectionsituationandinfluencefactorsofEBvirusinShundeRegionTIANNa-naPANJian-nanZHOUCheng-yuLUOMei-huaLVWei-biaoMAIRu_lanGAOYan-huiLIULiYUXin-faSchoolofPublicHealth，GuangdongPharmaceuticalUniversity;ShundeHospitalofSouthenMedicalUniversity;Abstract：Obj

4、ectiveTolearnabouttheepidemicsituationandinfluencingfactorsofEpstein-Barrvirus(EBV)infectioninthepopulationofShunderegion.MethodsQuestionnairesurveywasconductedon17727residentsofDaliang,ChencunandXingtantowninShunderegionfromApril2015toJune2015.Thelevelofnuclearantigen-1IgA(NA1-IgA)

5、andviralcapsidantigenIgA(VCA-TgA)ofEBviruswereexaminedbyenzyme-linkedimmunoassay(RLTSA).TheunconditionedlogisticregressionwasconductedtoexploretheinfluencefactorsofEBvirusinfection.ResultsAtotalof17581peoplewereselected.ThepositiverateofNAl-IgAand(VCA-IgA)ofEBviruswere3.23%and6.76%r

6、espectively.TheinfectionrateofEBviruswas9.49%.MenhaveahigherriskofEBvirusinfectionthanwomenwith0R=l.15(95%CI=1.04-1.28).Comparedwiththegroupofagebelow40yearsold,agebetween40to49reachedalowerriskwith0R=0.86(95%CI=0.73-1.01),whileafter50yearsold,therateofinfectionincreasedcontinuously

7、.Moreover，residentshavingahighdegreeofeducationobtainedalowriskofinfectionrate.Theinfectionrateofsmokerswashigherthannon-smokerswith0R=l.19(95%CI=1.01-1.39).ConclusionTheriskofEBvirusinfectioninmenishigherthanwomen，andthereisa“V”typeofrelationshipbetweenageandtheriskofEBvirusinfecti

8、on.Highdegreeofeduc