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ID:38565853
大小:301.00 KB
页数:61页
时间:2019-06-15
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1、TITLEDoestheTimingofPreoperativeEpiduralSteroidInjectionAffectInfectionRiskAfterACDForPosteriorCervicalFusion?术前硬膜外类固醇注射影响ACDF或PCF术后感染吗?StudyDesign.Aretrospectivedatabaseanalysis.研究设计:回顾性数据库分析。ABSTRACTObjective.Theaimofthisstudywastodeterminewhetheranyassociationex
2、istsbetweenpreoperativecervicalepiduralsteroidinjections(CESIs)atvarioustimeintervalsbeforeanteriorcervicaldiscectomyandfusion(ACDF)orposteriorcervicalfusion(PCF)andtheincidenceofpostoperativeinfection.目的:本研究的目的是确定术前颈椎硬膜外类固醇注射(CESIs)的不同的时间间隔与颈前路椎间盘切除融合术(ACDF)或颈椎后路融
3、合术(PCF)术后感染发生率的关系。ABSTRACTSummaryofBackgroundData.AlthoughinfectiouscomplicationsfollowingCESIareuncommon,theassociationbetweenpreoperativeCESIandpostoperativeinfectionfollowingACDForPCFhasyettobeevaluatedinthecurrentliterature.背景资料:虽然CESI后感染的并发症少见,但PCF或ACDF术前CESI与
4、术后感染之间的关联尚未在文献中进行报道。ABSTRACTMethods.Anationalinsurancedatabasewasutilizedtocomparepostoperativeinfectionrateswithin90daysinpatientswhoreceivedaCESIbeforeACDForPCF.Threecohortswerecreatedforeachprocedure:PCF(n=402)orACDF(n=4354)within3months,PCF(n=586)orACDF(n=5183)
5、between3and6months,andPCF(n=629)orACDF(3648)between6and12monthsfollowingaCESI.ThesecohortswerecomparedwithcontrolcohortswhounderwentPCF(n=61,253)orACDF(n=241,678)withoutpriorCESI.Postoperativeinfectionrateswithin90dayswereassessedusingInternationalClassificationofD
6、isease,9thRevision(ICD-9)andCurrentProceduralTerminology(CPT)codes.Oddsratios(ORs),95%confidenceintervals(95%CIs),andPvalueswerethencalculatedusingSPSS.Amultivariatebinomiallogisticregressionanalysiswasperformedtodeterminetheindependenteffectofpreoperativeinjection
7、onpostoperativeinfectionfollowingACDForPCFcontrollingforknownriskfactorsforinfection,includingage,gender,obesity,diabetes,andsmoking.方法:采用国家保险数据库的数据比较在ACDF或PCF之前接受CESI的患者在90天内的术后感染率。对于每个手术产生三个队列:3个月内的PCF(n=402)或ACDF(n=4354),3个月至6个月之间的PCF(n=586)或ACDF(n=5183)),在6和12个
8、月之间的ACDF(3648)或PCF(n=629)。将这些队列与在没有预先CESI的情况下接受PCF(n=61,253)或ACDF(n=241,678)的对照组进行比较。使用国际疾病分类第9版(ICD-9)和手术术语(CPT)代码评估术后90天内的感染率。然后使用SPSS计算比值比(OR)
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