letter to editor 回复编辑的信(sci)

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1、DearDr.XXX,Thankyouforarrangingatimelyreviewforourmanuscript.WearepleasedtoknowthatourstudyisofgeneralinterestforthereadersofNUTRITION.Wehavecarefullyevaluatedthereviewers’criticalcommentsandthoughtfulsuggestions,respondedtothesesuggestionspoint-by-point,andrevised

2、themanuscriptaccordingly.Allchangesmadetothetextareinredsothattheymaybeeasilyidentified.Withregardtothereviewers’commentsandsuggestions,wewishtoreplyasfollows:Enclosures:(1)Correspondencestoyourreviewers;(2)Onecopyoftherevisedmanuscript;(3)Afloppydiskcontainingther

3、evisedmanuscript.(4)CopyrightassignmentToreviewer　#11.TheauthorshouldaddafewreviewarticlesonghrelinforreadersintheIntroduction.Weaddedtworeviewsinourrevisedmanuscript.2.Theincreaseinghrelinlevelsdonotnecessaryindicatethatweightlossindiseaseiswellcompensated(Introdu

4、ctionandDiscussion).Thismaybeinterpretedtobeinsufficienttorecovertothepreviousbodyweight.Thereispossibilitythattheincreaseinghrelinlevelsmayresultfromtheinsufficienttorecovertothepreviousbodyweight,butitismorelikelythattheincreaseinghrelinlevelindicatethatweightlos

5、sindiseaseiswellcompensated.Shimizuetal1reportedthatbaselineplasmaghrelinlevelwassignificantlyhigherincachecticpatientswithlungcancerthaninnoncachecticpatientsandcontrolsubjects.Asweightlossisachronicprocessandghrelinlevelsmaychangemorerapidthanweightloss,theincrea

6、seinghrelininthosechronicdiseasesisunlikelyresultfromtheinsufficienttorecovertothepreviousbodyweight.Moreover,thisauthoralsoreportedthatfollow-upplasmaghrelinlevelincreasedinthepresenceofanorexiaafterchemotherapy,whichfurthersuggeststhattheincreaseghrelinlevelmayre

7、presentacompensatorymechanismundercatabolic–anabolicimbalanceincachecticpatientswithlungcancer1.3.TheauthorsshouldrefertotheoriginalreportthatIL-1bdecreaseplasmaghrelinlevels(Gastroentelorogy120:337-345,2001)Wereferredthisarticleasthereviewersuggested.Infact,thisis

8、amistakeofus.Manythanksforthereviewer’ssuggestion.4.Ref.13dosenotincludedataonghrelin.WearesosorrytomakethismistakeforcitingtheRef.13.Wereplacedt