bipap联合参麦注射液治疗重度心衰患者临床探究

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1、BiPAP联合参麦注射液治疗重度心衰患者临床探究【摘要】目的：研究无创双水平气道正压通气(BiPAP)联合参麦注射液对重度充血性心力衰竭的治疗效果。方法：41例重度充血性心力衰竭患者随机分为观察组(18例)和治疗组(BiPAP联合参麦注射液)（河北神威药业有限公司生产，国药准字Z1302O886）(23例),观察两组患者临床疗效和治疗前后的血气分析与心功能指标的改善情况。结果:治疗组有效率高于观察组，差异有显著性；治疗组氧分压(PaO2)、氧饱和度(SaO2)、心搏量、心脏指数和射血分数均明显高于观察组，二氧化碳分

2、压(PaCO2)和Boston积分均明显低于观察组，差异有显著性。结论：无创双水平气道正压通气(BiPAP)联合参麦注射液能提高重度充血性心力衰竭的治疗效果，值得临床推广。【关键词】无创双水平气道正压通气;参麦注射液;重度充血型心力衰竭【中图分类号】R541.6+1【文献标识码】A【文章编号】1007-8517(2009)12-0038-02Clinicalstudyoftherapeuticeffectofnoninvasivebi-levelpositiveairwaypressureventilationun

3、itedwithShenmaiinjectionon7thepatientswithseverecongestiveheartfailureWUMeng-zhangOUYANGDang-yu（DepartmentofEmergency,TheSecondXiangyaHospital,CentralSouthUiversity,Changsha,410011,China）【Abstract】Objective:ToResearchthetherapeuticeffectofnon-invasivebi-levelp

4、ositiveairwaypressure(BiPAP)combinedwithShenmaiinjectiononthepatientswithseverecongestiveheartfailure.Methods:41casesofseverecongestiveheartfailurepatientsarerandomlydividedintoobservationgroup(n=18)andtreatmentgroup(BiPAPUnitedwithShenmaiinjection)(n=23),twog

5、roups’therapeuticeffectandthedifferencesbetweentheresultsofcardiacfunctionandbloodgasanalysisbeforeandafterthetreatment，allofthoseareobserved.Results:Thetherapeuticeffectofthetreatmentgroupismuchgreaterthantheobservationgroup,andthedifferenceisasignificantone；

6、partialpressureofoxygen(PaO2)，oxygensaturation(SaO2)，strokevolume，ejectionfractionandcardiacindexinthetreatmentgroup7aresignificantlyhigherthanthoseintheobservationgroup，bycontraries，thepartialpressureofcarbondioxide(PaCO2)andBostonpointsintreatmentgrouparesig

7、nificantlylowerthanthoseintheobservationgroup，therearesignificantdifferences.ConclusionBiPAPcombinedwithShen-maiinjectioncanimprovethetreatment’sefficiencytotheseverecongestiveheartfailurepatients,anditisworthtobepopularized.【Keywords】BiPAP;Shen-maiinjection;s

8、everecongestiveheartfailure充血性心力衰竭(CHF)是一种复杂的临床证候群,是各种心脏病的严重阶段,其发病率、死亡率均高[1],治疗比较棘手。作者2006年3月～2008年3月采用无创双水平气道正压通气联合参麦注射液治疗重度充血性心力衰竭取得了较好的效果，现报道如下。1资料与方法1.1病例选择按Boston诊断标准[2],确诊为重度