资源描述：
《透明质酸the effects of hyaluronic acid on》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。
1、ResearchTheeffectsofhyaluronicacidonarticularchondrocytesM.Akmal,ThepurposeofthisstudywastoexaminetheeffectsofhyaluronicacidsupplementationA.Singh,onchondrocytemetabolisminvitro.Theclinicalbenefitsofintra-articularhyaluronicacidA.Anand,injectionsarethoughttooccurthroughimprovedjointlubrication.Recent
2、findingshaveA.Kesani,shownthatexogenoushyaluronicacidisincorporatedintoarticularcartilagewhereitmayN.Aslam,haveadirectbiologicaleffectonchondrocytesthroughCD44receptors.A.Goodship,Bovinearticularchondrocyteswereisolatedandseededintoalginateconstructs.TheseG.Bentleywereculturedinmediumcontaininghyalur
3、onicacidatvaryingconcentrations.Sampleswereassayedforbiochemicalandhistologicalchanges.FromtheInstituteofTherewasadose-dependentresponsetotheexposureofhyaluronicacidtobovineOrthopaedicsandarticularchondrocytesinvitro.Lowconcentrationsofhyaluronicacid(0.1mg/mLand1Musculoskeletalmg/mL)significantlyincr
4、easeDNA,sulphatedglycosaminoglycanandhydroxyprolineScience,RoyalFreesynthesis.ImmunohistologyconfirmedthemaintenanceofcellphenotypewithincreasedandUniversitymatrixdepositionofchondroitin-6-sulphateandcollagentypeII.ThesefindingsconfirmaCollegeMedicalstimulatoryeffectofhyaluronicacidonchondrocytemetabol
5、ism.SchoolandRoyalNationalOrthopaedicHospital,BrockleyTherapeuticeffortstotreatosteoarthritisareontheircellsurface;thishasthecapacitytoHill,Stanmore,usuallydirectedtowardsprovidingsymptom-functionasahyaluronicacidreceptorandsoEnglandaticreliefanddelayingtheneedfortotaljointmaybeinvolvedinbiochemical
6、interactionsarthroplasty.Recently,treatmentssuchaswithchondrocytes.14,15Theeffectsofhya-M.Akmal,MBBS,BSc,glucosamineandchondroitinsulphatesup-luronicacidinjectionsmaybemediatedviaFRCS(Orth),OrthopaedicSurgeonplementation,intra-articularinjectionofhya-CD44interactions.ExogenoushyaluronicacidA.Singh
7、,MBBS,BSc,luronicacid,1-3subchondraldrilling,mosaic-isknowntobeincorporatedintocartilage.16SeniorHouseOfficerA.Anand,MBBS,BSc,plasty,tissueengineeredfocaldefectrepairThepurposeofthisstudywastodetermin
