资源描述：
《水皰病之病理學探討 - 口腔病理》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。
1、水皰病之病理學探討-口腔病理口腔病理科BullousDiseases天??疾病?玉昆副教授:高雄??大?口腔病理科07-3121101~2755yukkwa@//0>.??目???目?水?病之病理?探?水?病之病理?探?水?形成的致病??水?形成的致病??天??天???天???天???考?料1.LeverWE:Histopathologyoftheskin.7thed.,p.116-312.SappJP:ContemporaryOral&illofacialPathology,p.254-603.KaohsiungMedicalUniversity,OralPath
2、ologyDepartment4.FislerREetal:Childhoodbullouspemphigoid-aclinicopathologicstudyandreviewoftheliterature.AmJDermatol2003;25:183-95.BaganJetal:Mucousmembranepemphigoid.OralDis2005;11:197-2186.BlackMetal:Pemphigusvulgaris.OralDis2005;11:119-307.RuoccoRetal:Life-threateningbullousdermatos
3、es:PemphigusvulgarisClinDermatol2005;23:223-68.RobinsonRAetal:Desquamativegingivitis:Asignofmucocutaneousdisorders?areview.AusDentJ2003;48:206-119.TilakaratneWMetal.Paraneoplasticpemphigus:acasereportandreviewofliterature.OralDis2005;11:326-910.//./imagepages/17280.htm11.WilliamsDM.Ves
4、iculobullousmucocutaneousdisease:pemphigusvulgaris.JOralPatholMed1989;18:544-5312.//./ostia/ijd/vol2n1/bullous.xml13.//..nz/immune/linear-iga.6>html14.//./Products/vb.php15.//./content/view/24/38/lang,en/16.DentClinNAm2005;49:107-125水?病之病理?探?水?病之病理?探?水?blister定?:表皮?水?blister定?:表皮?intra
5、epithelial或表皮下intraepithelial或表皮下subepithelial充?液?的空subepithelial充?液?的空腔,液?包含??液、血?、腔,液?包含??液、血?、和不同的?炎?胞。和不同的?炎?胞。空腔空腔空腔空腔Ref.3水?形成的致病??水?形成的致病??1.海??形成spongiosis1.海??形成spongiosis2.脊??解acantholysis2.脊??解acantholysis3.?胞溶解cytolysis3.?胞溶解cytolysis4.???性reticulardegeneration4.???性reticul
6、ardegeneration5.基底?胞膜?破?basement5.基底?胞膜?破?basementmembranezonedestructionmembranezonedestruction1.海??形成spongiosis1.海??形成spongiosis表皮??胞?水?表皮??胞?水?intercellularintercellularedema,使?胞之edema,使?胞之?堆?著?胞外液,?堆?著?胞外液,使得角??胞使得角??胞keratinocyte分隔,keratinocyte分隔,??小???小?desmosome分?,desmosome分?,形成
7、水?。形成水?。Ref.12.脊??解acantholysis2.脊??解acantholysis角??胞之?的??能力?角??胞之?的??能力?失。失。角??胞呈?形,?胞??角??胞呈?形,?胞??,?胞核大,染色?致密,,?胞核大,染色?致密,??核仁明?。核仁明?。EarlyAcantholyticcellsSinglecellsClustersLateRef.1,112.脊??解acantholysis2.脊??解acantholysisCausesofacantholysisPrimaryPemphigusDarier’sdiseaseTransie
