三七伤药胶囊口服加中药熏洗联合玻璃酸钠关节腔内注射治疗膝骨关节炎临床观察

《三七伤药胶囊口服加中药熏洗联合玻璃酸钠关节腔内注射治疗膝骨关节炎临床观察》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、三七伤药胶囊口服加中药熏洗联合玻璃酸钠关节腔内注射治疗膝骨关节炎临床观察【摘要】目的：观察三七伤药胶囊口服加中药熏洗联合玻璃酸钠关节腔内注射治疗膝骨关节炎的临床疗效。方法：将90例膝骨关节炎患者随机分为治疗组和对照组，每组45例。对照组采用玻璃酸钠关节腔内注射治疗，治疗组在对照组的基础上加用三七伤药胶囊口服及中药熏洗治疗。2组均以5周为1个疗程。观察2组临床疗效及KSS评分、W0MAC评分。结果：治疗组治愈31例，好转13例，未愈1例，总有效率为97.77%；对照组治愈16例，好转16例，未愈13例，总有效率为71.11%。2组比较，差异有统

2、计学意义（P〈0.05）。治疗后，2组KSS评分及W0MAC评分较治疗前均有改善（P〈0.05）,且治疗组优于对照组（P<0.05）。结论:三七伤药胶囊门服加屮药熏洗联合玻璃酸钠关节腔

3、A]注射可明显缓解膝骨关节炎患者的临床症状，值得临床推广应用。【关键词】骨关节炎，膝；骨痹；三七伤药胶囊；中药熏洗；玻璃酸钠[ABSTRACT]Objective：ToobservetheclinicalcurativeeffectofSanqiShangyaoJiaonang（三七伤药胶囊）andherbalfumigatingandwashingcombi

4、nedwithintraarticularinjectionofsodiumhyaluronatcinthetreatmentofknccostcoarthritis.Methods:90casesofkneeosteoarthritiswererandomlydividedintotwogroups：atreatmentgroupandacontrolgroup,45easesineachgroup.Thecontrolgroupwastreatedwithintraarticularinjectionofsodiumhyaluronate

5、,whilethetreatmentgroupwastreatedwithSanqiShangyaoJiaonangandherbalfumigatingandwashingbaseonthetreatmentforthecontrolgroup.The2groupsweretreatedfor5weeksasacourseoftreatment,observingtheirclinicalefficacy,KSSscoreandWOMACscore.Results：Inthetreatmentgroup,31caseswerecured,1

6、3caseswereimproved,and1casewasineffective,thetotalefficiencybeing97.77%；whileinthecontrolgroup,16caseswerecured,16caseswereimproved,and13caseswereineffective,thetotalefficiencybeing71.11%.Thedifferencewasstatisticallysignificantbetweenthe2groups(P<0.05).Aftertreatment,KSSsc

7、oreandWOMACscoreofthe2groupswereimproved(P<0.05)thanbeforetreatment,andthetreatmentgroupwasbetterthanthecontrolgroup(P<0.05).Conclusion:SanqiShangyaoJiaonangandherbalfumigatingandwashingcombinedwithintraarticularinjectionofsodiumhyaluronatecanrelievetheclinicalsymptomsofpat

8、ientswithkneeosteoarthritis,worthyofclinicalapplication.[Keywords]osteoarthritis,knee；bonerheumatism；SanqiShangyaoJiaonang(三七伤药胶囊)；herbalfumigatingandwashing；sodiumhyaluronate膝骨关节炎(kneeosteoarthritis,K0A)是指膝关节以软骨破坏为主要特征，由机械性损伤、代谢、炎症、自由基和免疫等多种因素参与造成的关节疾病。临床主要表现为膝关节频繁疼痛不适、软组织

9、肿胀、关节僵硬，甚至关节活动受限、强直、变形，患者日常生活及工作受到极大影响。近年来，KOA的发病率逐年升高，冃前尚无统一而有效的治疗方法。根据中国知网和万方数据的