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1、红景天注射液治疗慢性阻塞性肺疾病急性加重期疗效观察【摘要】日的：观察人株红景天注射液配合常规治疗对慢性阻塞性肺疾病急性加重期（AECOPD）患者临床疗效的影响。方法：将60例AECOPD患者随机数字表法分为治疗组与对照组，各30例，均予常规治疗，治疗组加用大株红景天注射液静滴，疗程为10d。观察两组患者临床症状及客观检查指标，用药前后行血气分析检查。结果：治疗组总冇效率高于对照组（P〈0.05）。治疗组动脉血氧分压高于对照组（P〈0・05）,二氧化碳分压低于对照组（P〈0.05）。结论：在常规治疗的基础上联川大株红景天注射液治疗AECOPD能明显提高临床疗
2、效。【关键词】慢性阻塞性肺疾病急性加重期；大株红景天注射液；疗效TherapeuticEffectofSofrenInjectioninTreatmentofAcuteExacerbationsofCOPD/QUQiu,XUJian,LIShu-yun.//MedicalInnovationofChina,2014,11(32)：014-016[Abstract]Objective：ToobservetheclinicaleffectofSofreninjectioncombinedwithconventionaltreatmentsonacuteexac
3、erbationsofCOPD(AECOPD)・Method：Atotalof60patientswithAECOPDwererandomlydividedintothetreatmentgroupandthecontrolgroup,eachgroupcontained30cases,twogroupsweregivenconventionaltreatment,andthetreatmentgroupwereaddedSofreninjectionintravenousdrip,thecourseoftreatmentwas10days・Thechan
4、gesofclinicalsymptomsandobjectiveindexesbeforeandaftertreatmentwereobservedinbothgroups.Thearterialbloodgasesofpatientsinthetwogroupsbeforeandaftertreatmentweredetermined.Result:Theefficiencyofthetreatmentgroupwassignificantlyhigherthanthatofthecontrolgroup,thediffereneewassignifi
5、cant(P<0.05)・Thearterialpartialpressureofoxygenofpatientsofthetreatmentgroupaftertreatmentwassignificantlyhigherthanthatofthecontrolgroup(P<0.05)・Thearterialpartialpressureofcarbondioxideofpatientsofthetreatmentgroupaftertreatmentwassignificantlylowerthanthatofthecontrolgroup(P<0.
6、05)・Conclusion：CombinedwithSofreninjectiononthebasisofconventionaltreatmentintreatmentofAECOPDcanobviouslyimprovetheclinicalcurativeeffect・[Keywords]AECOPD；Sofreninjection；CurativeeffectFirst-authot'saddress:TheFirstAffiliatedHospitalofKunmingMedicalUniversity,Kunming650032,Chinad
7、oi:10.3969/j.issn.1674-4985.2014.32.005慢性阻塞性肺疾病(chronicobstructivepulmonarydisease,COPD)是一种发病率非常高而口严重影响患者生活质量的疾病，它所导致的肺功能下降常常伴随着缺氧的发生，而缺氧会对人体的各个系统的机能造成影响，严重者致残甚至危及生命。目前尚无明确的能有效抗缺氧的化学药物,因此研究具有抗缺氧作用的中药制剂，有着重要的意义。近年来中药红景天制剂在抗缺氧损伤的研究屮取得一定进展［1］。笔者在常规治疗的基础上加用大株红景天注射液静滴辅助治疗慢性阻塞性肺疾病急性加重期（
8、AcuteexacerbationsofCOPD,AECOPD）,
