fabrcation and characterization of highly potent silverorganoalkoxysilane antimicrobial nanofibers and antibacterial studies of its components

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1、学位论文数据集中图分类号学科分类号论文编号密级学位授予单位10010学位授予单位代码名称北京化工大学作者姓名SirajoUmar学号2007020008获学位专业名获学位专业代称码课题来源研究方向ThefabricationofHighlyPotentSilver—Organoalkoxysilane论文题目Nano—fibersandtheantibacterialStudiesofitScomponents关键词宰论文类论文答辩日期2013／05／21型学位论文评阅及答辩委员会情况姓名职称工作单位学科专长Chen指导教师BUCTJinchun评阅人1

2、评阅人2评阅人3评阅人4评阅人5答辩委员会主席LiGuantaoQinghuaUniv．答辩委员1LiGuantaoQinghuaUniv．答辩委员2YuanQifengBUCTProcesS答辩委员3YuanFengliEngneering，CASInstituteof答辩委员4WangTaiBotany，CAS答辩委员5MaRunyuBUCT注：一．论文类型：1．基础研究2．应用研究3．开发研究4．其它二．中图分类号在《中国图书资料分类法》查询。三．学科分类号在中华人民共和国国家标准(GB／T13745-9)((学科分类与代码》中查询。四．论文编号由

3、单位代码和年份及学号的后四位组成。AbstractWeusedasimpleelectrospinningtechniquetofabricateahighlypotentsilver-organoalkoxysilanesantimicrobialcompositefromethanol·-AgN03··polyvinylpyrrolidone／3--aminopropyltrimethoxysilane／tetraethoxysilane(AgN03-PVP／APTMS／TEOS)solution．Spectroscopicandmicroscopi

4、canalysesofthecompositeshowedthatthefiberscontainorganoalkoxysilanes‘‘skeleton'’，O．18molecules／nm2surfaceaminogroups，andhighlydispersedanduniformlydistributedsilvernanoparticles(5nminsize)．Incorporationoforganoalkoxysilanesishi曲lybeneficialtotheantimicrobialmatas：-1)aminogroupsof

5、APTMSareadhesiveandbiocidaltomicroorganisms，2)polycondensationofAPTMSandTEOSincreasesthemembrane’Ssurfaceareabyformingsiliconbondsthatstabilizefibersandformcompositematwithmembranousstructureandhighporosityand3)theorganoalkoxysilanesarealsoinstrumentaltothesynthesisoftheverysmall

6、sizedandhighlydispersedsilvermetalparticlesinthefibermat．Themembraneshowsquickandsustainedbroadspectrumantimicrobialactionagainstbacteria饵coli,B．anthracis,S．aureusandB．suis)，fungi∽．niger)andNewcastlediseasevirus(LaSotastrain)．Only0．3mgofthefibersisrequiredtoachieveminimuminhibiti

7、onconcentration(MIC)BeijingUniversityofChemicalTechnolohyPhDThesisagainstallthetestorganisms．Bacteriaareinhibitedwithin30minutesofcontactandthefiberscanbeusedrepeatedly．Thecompositemayfindapplicationinairfilters，antimicrobiallinen，coatings，bioadhesiveandbiofilm．Owingtotheremarkab

8、leantimicrobialpropertyobservedwithallth