纯钛种植体激光—微弧氧化表面改性的骨结合效能的研究

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1、Theroleofpuretitaniumimplantsurfacemodifiedbylaserandmicro-arcoxidationonosseointegrationAbstractObjectiveToevaluatetheimplantsurfacepropertiesaftermodifiedbYlaseretchingandmicro．aleoxidation,andtestifywhethertheimplantsmodifiedbylaseretchingandmicro．arcoxidationhaveexcellentBiocompatibility

2、andOsteo-conductiveornot．MethodsPart1manufactureandsurfacemodificationofthepuretitaniumscrewimplantPuretitaniumScrewimplantweremanufacturedbyselectedpuretitanium’material,thediameterandshapesweresimilartotheimplantappliedinclinic．Alloftheseimplantswerepackedafterultrasoniccleaning．Differents

3、urfacemodificationsofthepuretitaniumscrewimplantsweredividedintofourgroups：1．Controlgroup：PuretitaniumScrewimplantswithmachinesurface．2．Lasergroup：PuretitaniumScrewimplantswereirradiatedbylaser．3．MAOgroup：PuretitaniumScrewimplantsweremodificatedbymicro’arcoxidation．4．Laser／MAOgroup：Puretitan

4、iumscrewimplantswereirradiatedbylaser,andthenmodificatedbymicro-arcoxidation．Severallaboratoryapparatuswereusedtodetectthepropertiesofthefourgroupsofimplants．Alloftheimplantswerepackedafterultrasoniccleaningandsterilizedunderthehightemperatureandhighpressure．4Part2Theroleofimplantmodifiedbyl

5、aserandmicro—arcoxidationonOsseointegration’24maleadultNewZealandrabbitswithweightrange2．5．-,3．Okgweredividedintofourgroupsaccordingtotherandomprinciples：Controlgroup、Lasergroup、MAOgroupandLaser／MAOgroup．Fourkindsofimplantswithdifferentsurfacedeahngwereinsertedincirca-epiphysisoftibiaoftheco

6、rrespondingrabbits．Aftertheoperation,fouroftherabbitsweresacrificedfortnightlytoobtajlnthebonesamples．Beforesacrificing，aurabbitswerehypodermicinjectedwithfluorescently-labeledacheomycinandcalcein．AUbonesampleswereembeddedbyplasticembeddingtechniqueswithoutdecalcifying，andthencuttobeslicesab

7、out200micronsbytheLeicaSP1600saWmicrotomeandgroundtoabout70micronsbyhand．Afterspecialgaining，thebone-implantinterfaceswereobservedthroughthemicroscope，andtheexperimentaldatawasanalyzedbySPSS13．0．Resultsl1．Controlgroup：Puretitaniumimplantswithmachin