隔姜蒜督灸治疗强直性脊柱炎及对血清骨钙素影响的临床研究

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1、提要目的：观察隔姜蒜督灸治疗强直性脊柱炎的临床疗效及不良事件发生情况，分析隔姜蒜督灸对血清骨钙素的影响，为强直性脊柱炎的治疗提供新的方法。方法：筛选60例强直性脊柱炎患者，随机分为治疗组与对照组。治疗组采用隔姜蒜督灸治疗，对照组采用隔姜督灸治疗。每组30例患者，治疗三次，每月一次，分别观察患者治疗前后症状、体征和试验指标骨钙素的变化。结果：1．两组治疗前后症状积分组内比较均有非常显著性差异（P＜0.01）；治疗后组间比较有显著性差异（P＜0.05）,治疗组优于对照组。2．两组治疗前后体征积分组内比较均有显著性差异（P＜0.05），治疗后两组间比较无差异

2、（P＞0.05）。3．两组治疗前后骨钙素组内比较有非常显著性差异（P＜0.01），治疗后两组间比较有显著性差异（P＜0.05）。4.两种治疗方法均可有效改善临床症状（P＜0.05），治疗组总有效率为90%；对照组总有效率为80%。5.观察期间治疗组和对照组均无不良事件发生。结论：隔姜蒜督灸可改善强直性脊柱炎患者的临床症状、体征，显著降低血清骨钙素的数值，且在本次研究中无不良事件发生，是治疗强直性脊柱炎安全有效的方法之一。关键词隔姜蒜督灸；强直性脊柱炎；骨钙素；不良事件TheClinicalResearchoftheInfluenceofDu-Moxib

3、ustionacrossGingerandGarlictoBoneGammainTreatingASSpeciality：AcupunctureandMoxibustionAuthor：SongpanTutor：ZhangtongAbstractObject:ToobservetheclinicalcurativeeffectandadverseeventsofDu-MoxibustionacrossgingerandgarlicintreatingAnkylosingSpondylitis(AS),thisstudyistoanalyzetheimp

4、actevaluationoftheBGP,andtoexploreanewideaandwayfortreatmentofAS.Method:60patientswithASweredividedintotreatmentgroupandcontrolgroupatrandom.30casesweretreatedwithDu-Moxibustionacrossgarlicandgingertherapy,whiletheother30casesweretreatedwithDu-Moxibustionacrossgingertherapy.Each

5、groupwastreated3timesinallandwastreatedonceamonth.Thechangesofsymptoms,signsandBGPofpatientswereobservedbeforeandafterthetreatmentandanalyzedwithstatisticmethodtodrawconclusions.Result:1.Symptom-scorecomparisonbeforeandafterthetreatmenthadagreatlysignificantdifference(P<0.01)ine

6、achgroup,comparisonbetweenthetwogroupshadsignificantdifference(P<0.05),andthetreatmentgroupisbetterthanthecontrolgroup.2.Sign-scorecomparisonbeforeandaftertreatmentshowedsignificantdifference(P<0.05)ineachgroup,comparisonbetweenthetwogroupsshowednosignificantdifference(P>0.05)af

7、terthetreatment.3.BGPbeforeandafterthetreatmenthadverysignificantdifferences(P<0.01)ineachgroup;betweenthetwogroupstherewasasignificantdifferences(P<0.05).4.Bothofthetwomethodscanimprovetheclinicalsymptoms(P<0.05)effectively,Theefficientrateofthetreatmentgroupwas90％andthecontrol

8、groupwas80％.5.Neitherthetreatmentgroupnorthecon