资源描述：
《Kaldis_Cell Cycle Regulation(2005).pdf》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。
1、ResultsandProblemsinCellDifferentiation42SeriesEditorsD.Richter,H.TiedgePhilippKaldis(Ed.)CellCycleRegulationWith26Figures,1inColor,and9Tables123PhilippKaldis,PhDNationalCancerInstitute,NCI-Frederick1050BoylesStreetBldg.560Frederick,MD21702-1201USAISSN0080-1844ISBN-103-540-34552-3SpringerBerl
2、inHeidelbergNewYorkISBN-13978-3-540-34552-7SpringerBerlinHeidelbergNewYorkLibraryofCongressControlNumber:2006925965Thisworkissubjecttocopyright.Allrightsarereserved,whetherthewholeorpartofthematerialisconcerned,specificallytherightsoftranslation,reprinting,reuseofillustrations,recitation,broad
3、-casting,reproductiononmicrofilmorinanyotherway,andstorageindatabanks.DuplicationofthispublicationorpartsthereofispermittedonlyundertheprovisionsoftheGermanCopyrightLawofSeptember9,1965,initscurrentversion,andpermissionforusemustalwaysbeobtainedfromSpringer.Violationsareliableforprosecutionund
4、ertheGermanCopyrightLaw.SpringerisapartofSpringerScience+BusinessMediaspringer.comcSpringer-VerlagBerlinHeidelberg2006PrintedinGermanyTheuseofregisterednames,trademarks,etc.inthispublicationdoesnotimply,evenintheabsenceofaspecificstatement,thatsuchnamesareexemptfromtherelevantprotectivelawsan
5、dregulationsandthereforefreeforgeneraluse.Coverdesign:Design&ProductionGmbH,HeidelbergTypesettingandProduction:LE-TEXJelonek,Schmidt&VöcklerGbR,LeipzigPrintedonacid-freepaper31/3150/YL–543210PrefaceThecellcycleistightlyregulatedonmanydifferentlevelstoensureproperlycontrolledproliferation.Inth
6、elast20years,throughthecontributionsofmanylaboratories,wehavegainedinsightintomanyimportantaspectsoftheregulationofthecellcycleanditsrelationtocancer,whichculminatedinthe2001NobelPrizebeingawardedtoLelandHartwell,TimHunt,andPaulNurse.Intheinvestigationsofcellcycleregulation,ithasbeenessential
7、tousedifferentmodelsystemsfromyeasttomouse,wheretheresultsfromonesystemhaveledtoadvancesinanothersystem.Recently,studieshavebeendoneusingmorecomplexorganismslikethemouse,whichhastaughtusmuchaboutredundancyandflexibilityintheregulationofthecell
