5-ht及其受体在异氟烷麻醉—觉醒调节中的作用及机制

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1、分类号R614.1UDC616-08密级公开5-HT及其受体在异氟烷麻醉-觉醒调节中的作用及机制欧阳鹏荣培养类别全日制学位类型专业学位一级学科(专业类)临床医学二级学科(专业)麻醉学研究方向全麻机制指导教师董海龙培养单位西京医院麻醉科二O一五年五月第四军医大学硕士学位论文目录缩略语表······························································································1中文摘要·······················

2、·······································································3ABSTRACT··························································································8前言···························································································

3、··14文献回顾·····························································································16正文·····························································································24实验一侧脑室微注射5-HT及其受体激动剂/拮抗剂对异氟烷麻醉觉醒的影响··241材料······················

4、·····································································241.1动物····················································································241.2药品与试剂···········································································241.3主要仪器··········

5、····································································252方法···························································································252.0实验设计···············································································252.1微注射套管的定

6、位埋置和固定····················································262.2异氟醚麻醉和翻正反射观察方法·················································263结果···························································································29实验二PEF微注射5-HT1A受体激动剂/拮抗剂对异氟烷麻醉觉醒的影响·····

7、····331材料···························································································331.1动物······················································································331.2药品与试剂·····························································

8、················331.3主要仪器················································································342方法··········································