萘酰亚胺噻唑类新化合物的设计合成与抗微生物作用相关研究

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1、符号说明符号说明英文缩写英文名称中文名称IRInfraredspectroscopy红外光谱NMRNuclearmagneticresonance核磁共振MSMassspectrometry质谱HRMSHighresolutionmassspectrometry高分辨质谱S.aureusStaphylococcusaureus金黄色葡萄球菌MRSAMethicillinresistantstaphylococcusaureu甲氧西林耐药金黄色葡萄球菌S.aureus25923Staphylococcusaure

2、usATCC25923金黄色葡萄球菌ATCC25923S.aureus29213StaphylococcusaureusATCC29213金黄色葡萄球菌ATCC29213E.faecalisEnterococcusfaecalis粪肠球菌K.pneumoniaKlebsiellapneumonia肺炎克雷伯氏杆菌E.coliEscherichiacoli大肠杆菌E.coli25922EscherichiacoliATCC25922大肠杆菌ATCC25922A.baumaniiAcinetobacterbauma

3、nii鲍曼不动杆菌P.aeruginosaPseudomonasaeruginosa铜绿假单胞菌P.aeruginosa27853PseudomonasaeruginosaATCC27853铜绿假单胞菌ATCC27853C.albicansCandidaalbicans白色念珠菌C.tropicalsCandidatropicals热带假丝酵母菌A.fumigatusAspergillusfumigates烟曲霉菌C.albicans90023CandidaalbicansATCC90023白色念珠菌ATCC9

4、0023C.parapsilosis22019CandidaparapsilosisATCC22019近平滑念珠菌ATCC22019HSAHumanserumalbumin人血清白蛋白DMSODimethylsulfoxide二甲亚砜DMFN,N-DimethylformamideN,N二甲基甲酰胺Tris2-Amino-2-(hydroxymethyl)-1,3-propanediol三羟甲基氨基甲烷MICMinimuminhibitoryconcentration最低抑菌浓度TLCThinlayerchr

5、omatography薄层色谱Contents中文摘要.....................................................................................................................IAbstract.........................................................................................................

6、..................IV第一章萘酰亚胺噻唑类化合物在抗细菌和抗真菌领域研究新进展以及论文选题1Chapter1Recentresearchesandapplicationsofnaphthalimidethiazolederivativesasantibacterialandantifungalagentsandstrategyofthisthesis..........................................11.1Introduction...............

7、..............................................................................................41.2Newadvanceofnaphthalimidesasantibacterialandantifungalagents.................51.2.1Naphthalimidesasantibacterialagents..........................................

8、...................51.2.2Naphthalimidesasantifungalagents................................................................81.3Recentprogressofthiazolederivativesasantibacterialandantifungalagents