新型黄连素唑类衍生物的设计合成及其抗微生物活性研究

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1、Contents中文摘要.....................................................................................................................IABSTRACT...................................................................................................................III第一章黄连素类化合物的结构修饰与抗微生物研究新进展及论文选题...

2、.............1Chapter1Recentadvanceinthestructuralmodificationandantimicrobialresearchofberberinesandstrategyofthisthesis..................................................................11.1Introduction......................................................................................

3、..........................................41.2Structuralmodificationofberberines.........................................................................................51.2.1Modificationat8-position..........................................................................................

4、................51.2.2Modificationat9-position..........................................................................................................81.2.3Modificationat12-position......................................................................................................161.

5、2.4Modificationat13-position......................................................................................................181.2.5Modificationatmultiplepositions............................................................................................201.3Antibacterialagents.....

6、............................................................................................................231.3.1Berberinederivedtriazoles.......................................................................................................251.3.2Berberinederivedimidazoles.............

7、......................................................................................261.3.3Berberinederivedbenzimidazoles............................................................................................271.3.4Otherberberines.............................