Neurology-2012-How well do blood flow imaging and collaterals on angiography predict brain at risk

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1、Howwelldobloodflowimagingandcollateralsonangiographypredictbrainatrisk?DavidS.LiebeskindandNersesSanossianNeurology2012;79;S105DOI10.1212/WNL.0b013e3182695904ThisinformationiscurrentasofSeptember24,2012Theonlineversionofthisarticle,alongwithupdatedinformationandservices,islocatedontheWorldWideWeb

2、at:http://www.neurology.org/content/79/13_Supplement_1/S105.full.htmlNeurology®istheofficialjournaloftheAmericanAcademyofNeurology.Publishedcontinuouslysince1951,itisnowaweeklywith48issuesperyear.Copyright©2012byAANEnterprises,Inc.Allrightsreserved.PrintISSN:0028-3878.OnlineISSN:1526-632X.Howwell

3、dobloodflowimagingandcollateralsonangiographypredictbrainatrisk?DavidS.Liebeskind,MDABSTRACTNersesSanossian,MDAsendovasculartherapyemergesasaprincipalapproachtorestorebloodflowinthesettingofacutestroke,bettermethodsofpatientselectionneedtobedeveloped.Noninvasivestudiesofbloodflowandangiographicre

4、sultsacquiredpriortoendovasculartherapymayhelpdetermineCorrespondence&reprintrequeststoDr.Liebeskind:areasofbrainatriskofinfarctionandhemorrhagictransformation,bothlargelydeterminedbythedavidliebeskind@yahoo.comseverityofcerebralischemia.Pathophysiologicmeasuresofcollateralflowandperfusionthatcha

5、racterizeischemicseveritypriortorevascularizationmayoptimizeacutestrokedecision-making,currentlydrivenbyarbitrarytimeparametersderivedfrompopulationstudiesdevoidof®imaging.Neurology2012;79(Suppl1):S105–S109GLOSSARYASITN/SIR
AmericanSocietyofInterventionandTherapeuticNeuroradiology/SocietyofInterv

6、entionalRadiology;CBF
cerebralbloodflow;CBV
cerebralbloodvolume;CTA
computedtomographicangiography;CTP
computedtomographicperfusion;MCA
middlecerebralartery;MRA
magneticresonanceangiography;PWI
perfusion-weightedMRI;SIR
SocietyofInterventionalRadiology;SVIN
SocietyofVascularandInterventionalNeuro

7、logy;TTP
timetopeak.Thelastdecadehasseennumerousadvancesinneuroimagingandacuteischemicstrokethera-pies,1,2withtheemergenceofendovasculartherapyasaprincipalapproachtobloodflowrestoration.Definingtheoptimalconditionsforr