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1、sci论文常用句型摘抄1.Takentogether,ourdataprovidenewmechanisticinsightsintopossibleendogenoussignalingmetastaticsignalingpathwaysinvolvedinmaintainingproliferationandmigrationofbreastcancercells.2.Wesoughttodeterminewhetherseliciclib(CYC202,R-roscovitine)couldincreaset
2、heantitumoreffectsofdoxorubicin,withnoincreaseintoxicity,inanMCF7breastcancerxenograftmodel.3.MIB1(ki67)immunohistochemistrydemonstratedreducedproliferationwithtreatment.(用于ki67方面)4.Survivinembodiestheseproperties,and5.Moreover,inpre-clinicalbladdertumormodels,
3、inhibitionofSurvivinexpressionand/orfunctionhasbeenshowntoimpedetumorcellproliferation,andmarkedlyinducespontaneousorchemotherapyinducedapoptosis6.Theefficacyofmainstaycancertherapies,cytotoxicsandradiation,hasreachedaplateauinthetreatmentofmanycancers,andthere
4、isanurgentsensethatimprovementsmustnowcomefromfreshapproaches.7.Medianagewas62yearswitharangeof40-74years.8.splicevariantsmightfunctionineffectasdominantnegativessothattheirexpressionmightconcurrentwithsurvivin.9.Thereisahypothesisthat10.Theabsenceofinvivodatao
5、nthispointhasnowbeenremediedwithapaperinthisissueoftheJCIbyAltieriandcolleagues.11.Thus,thisraisesaninterestingquestionwhether...12.raisingthepossibilitythatmost,ifnotall,tumorsexpress...13.Thelevelsofp21andp27increasedaftertreatmentwithdoxorubicinorselicicliba
6、loneorincombination,comparedtountreatedcontrols.14.Incontrast,itisabundantlyexpressedinawidevarietyofmalignanttissues.15.Onthecontrary,...16.Bycontrast,agoodtitlewillattracttherelevantresearchersandincreasethenumberofcitationsyoureceive17.Wehavefoundthatthehuma
7、nbreastcancercellsMCF-7/AdroverexpressnotonlyP-gpbutalsoXIAPandSurvivin,andshowedhighresistancetochemotherapeuticdrugsdoxorubicin,docetaxelandvincristine,incontrasttotheirparentalcellsKBandMCF-7.18.Survivinisaberrantlyexpressedinvariouskindsofcancercellsbutisun
8、detectableinnormaldifferentiatedadulttissues,withtheexceptionoftestis,thymus,andplacenta.19.TheattributablemortalityofCVCrelatedbloodstreaminfectionsrangesfrom0%to11.5%,20.G
