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1、GLOBALJOURNALOFPUREANDAPPLIEDSCIENCESVOL15,NO.3,2009:365-368365COPYRIGHT©BACHUDOSCIENCECO.LTDPRINTEDINNIGERIA.ISSN1118-057ANTIBACTERIALACTIVITYANDMEDICINALPROPERTIESOFGINGER(zingiberofficinale)S.P.MALU,G.O.OBOCHI,E.N.TAWOANDB.E.NYONG(Received20,June2008;RevisionAccepted6,November2008)A
2、BSTRACTTheantibacterialactivityandmedicinalpropertiesofgingerextractswerestudied.Gingerextractswereobtainedusingsolvents,n-hexane,ethylacetate,ethanolicsoxhletandwater.Theextractswereassayedforantibacterialactivityandbacterialgrowthinhibitionactivity.Theresultsshowedthatalltheextractse
3、xceptthewaterextracthaveantibacterialactivityandthattheinhibitionofbacterialgrowthwasdosedependent.Theresultsalsoshowedthatgingerextractspossessesantibacterialpropertiesandcouldbeusedforthetreatmentofbacterialinfections.KEYWORDS:Ginger,Antibacterialactivity,inhibitionofbacterialgrowth,
4、medicinalpropertiesandbacterialinfections.INTRODUCTIONthroughouttheworld.ThegingerplanthasalonghistoryofcultivationknowntooriginateinChinaandthenGinger(zingiberofficinale),RoscoebelongingtospreadtoIndia,SouthEastAsia,WestAfricaandthetheFamilyZingiberaceae,isaperennialherbwiththickCarib
5、bean(Weiss,1997;McGee,2004).Gingertuberousrhizomes.Theerectleafyaerialstemgrowsupcontainsupto3%ofanessentialoilthatcausesthetoapproximately1meterinheightandhaspurplefragranceofthespice(O’Haraetal,1998).Themainflowers(fig.1).Itsrootsareusedasspiceincookingconstituentsaresesquiterpenoids
6、with(-)-Figure2:Athicktuberousrhizomeofgingerroot.Figure1:Anerectstemofgingerzingiberofficinale)zingibereneasthemaincomponent.OthercomponentsThepungenttasteofgingerisduetonon-includeβ-sesquiphellandrenebisaboleneandfarnesenevolatilephenylpropanoid–derivedcompounds,whicharealsosesquiter
7、penoids,(β-sesquiphellandrene,gingerolsandshogaols.Theshogaolsareformedfromcineolandcitral)(Opdyke,1974;O’Haraetal,1998).gingerolswhengingerisdriedorcooked.ZingeroneisS.P.Malu,Departmentofchemistry/Biochemistry,CrossRiverUniversityofTechnology,Calabar.G.O.Obochi,Departmentofchemistry
