瘤周水肿明显的脑膜瘤术后高压氧治疗

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1、万方数据·138·瘤周水肿明显的脑膜瘤术后高压氧治疗唐晓平张涛彭华余定庸唐文国漆建罗仁国冯凌王远传苟章洋陈灵梅才君【摘要】目的探讨高压氧(HBO)在瘤周水肿明显的脑膜瘤术后的治疗作用。方法将232例瘤周水肿明显的脑膜瘤根据术前、术后平衡的原则分为HBO治疗组和对照组，各116例。HBO治疗组在对照组治疗的基础上，早期应用高压氧治疗，术后半个月统计两组患者的机能状态(KPS评分)、术区水肿体积，术后半年统计两组患者术区异常密度影体积和神经功能障碍例数，并做统计学分析。结果两组患者术后3dKPS评分及术区水肿体积差异无统计学意义(P

2、>O．05)；术后半个月HBO治疗组KPS评分高于对照组，术区水肿体积明显小于对照组，两组比较差异有统计学意义(P<0．05)；术后半年HBO治疗组术区异常密度体积小于对照组(P

3、abyhyperbaricoxygenation8ftertumorectomyTANGXiao-ping，ZHANGTao，PENGHna，YUDing—y0，培，TANGWen-guo，QtJian，LUORen—guo，FENG幻曙，WANGYuan-chuan，GOUZhang—yang，CHENLing，MEICai-ju几TheA够liatedHospital，NorthSichuanUniversityofMedical&icnces，Nanchong637000。China【Abstract】ObjectiveT

4、oexploretheeffectofhyperbaricoxygen(HBO)ontreatingmeningeomawithperitumoralbrainedemaaftertumorectomy．MethodsAccordingtotheprincipleofholdingthebalanceofpreoperativeandpostoperative，theclinicaldataof232patientswithperipheraledemaaroundmeningeomaweredividedintoexperim

5、entalgroupandcontrolgroup．thateachwerel16cases．HBOtherapywasearlyappliedinexperimentalgroupandothertherapywasconformedtocontrolgroup．Thefunctionstate(KPSscore)，operativeregionaledemavolumeofthesegroupswereperformedinductivestatisticsathalfmonthsaftertumorectomy．Theca

6、sesofabnormaloperativeregionaldensityimageandneurofunctionaldisturbanceathalfyearsafteroperationwereanalyzed．ResultTheKPSscoreandoperativeregionaledemavolumehavenosignificantdifferencebetweenthesetwogroups3daysafteroperation(P>0．05)；theKPSscoreofexperimentalgroupwash

7、igherthancontrolgroupathalfmonths，anditsedemavolumewassmaller(P<0．05)；theoperativeregionaledemavolumeofexperimentalgroupwassmallerthancontrolathalfyears(P<0．05)，andtheexamplesofexperimentalgroupwhohadgeneratedepilepsy，aphasia，incompleteparalysisweresmallerthancontrol

8、group(P<0．01)．ConclusionThemeningeomawithsignificalperipheraledemashouldbeapplicatedearlyHBOtherapyaftertumorectomy，andthatoftenobt