Modern Methods of Particle Characterization

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1、TheElzoneII5390TheElzoneII5390ParticleCountandSizeAnalyzerElzoneIIOverviewofBasicTheory•OperatesusingtheElectricalSensingZone(ESZ)Principle,alsoknownastheCoulterPrinciple.•FirstcommerciallyavailableElzonesystemwasintroducedin1963.•FullycomplianttotheISO13319Standard-DeterminationofPartic

2、leSizeDistributions-ElectricalSensingZoneMethod,aswellasnumerousASTMmethods.•Technologyhasbeenstandardizedforuseinautomatedbloodcellcountersaswellasacharacterizationmethodformanybiologicalandindustrialproducts.•ThousandsofreferencesfortheuseofvariousElectricalSensingZonemodelsdocumented.

3、•Thehighestresolutiontechnologyavailableforparticlecountingandsizing.ElzoneIIOverviewofBasicTheory•IndividualParticleSizeandConcentrationareMeasured.Notcalculated.•Particlesizeisrepresentedastheequivalentsphericalvolumediameter.•Operationisnotaffectedbycolorofsampleorrefractiveindexes(as

4、iswhenusingotheranalyticalmethods).•Capableofperformingcountandsizeofverylowconcentrationsamplesifnecessary.•Particleconcentrationisdeterminedusinganaccuratemeteringdevice.•Dynamicsizemeasurementsaremadeinrealtime.•Capableofperforminganalyseswithsamplessuspendedinanaqueousbuffersolutiono

5、rhazardousdiluents.ElzoneIIOverviewofBasicTheory•Particlessuspendedinanelectrolytesolutionaredrawnthroughasmallaperture.Acrosstheapertureavoltageisapplied.Thiscreatesthe“sensingzone.”•Particlespassingthroughtheaperturedisplaceavolumeofelectrolyticsolutionequaltotheparticle’sownvolume.•Di

6、splacedelectrolytecausesachangeinresistanceacrosstheapertureresultinginavoltagepulse.•Pulseintensityisproportionaltotheparticlevolume.ElzoneIIOverviewofBasicTheory–SensingZoneandPulseGenerationSensingZone11109845673•Asparticlesapproachandpassthrough2theElectricalSensingZone,apulseis1gene

7、rated.•ThepulseinformationisusedtocountandParticleenteringsizeparticles.theSensingZone•Individualpulsedataisstoredasafingerprintenablinguserstoextractadditionalinformationabouttheirsample.Uniquefingerprintofeachparticleis1234567891011captured.ElzoneIIFeaturesandBenefits•A