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1、SupportedbyJanssenreportcover.indd107/01/201313:23:46ThesilentpandemicTacklinghepatitisCwithpolicyinnovationContentsExecutivesummary2Aboutthisreport4Anicebergloominginafogofuncertainty5BarrierstotacklingHCV10Findingawayforward14Conclusion201©TheEconomistIn
2、telligenceUnitLimited2012ThesilentpandemicTacklinghepatitisCwithpolicyinnovationExecutivesummaryHepatitisCmaybetheseriousdiseasethatmostso-calledend-stageconditions.IntheUS,forcombineswidespreadprevalencewithwidespreadexample,HCVnowaccountsformoredeathstha
3、nignorance.AccordingtotheWorldHealthHIV,and82%ofthosewiththeformerdiseaseOrganisation(WHO),thisurgentpublichealthareamongthosebornbetween1945and1965.problemkills350,000peopleperyear,and150Expertsagree,however,thattypicallyonlyamillionhavethechronicformofth
4、ehepatitisCminorityofthosewithHCVhavebeendiagnosed,virus(HCV).Theincidenceofnewinfectionsisandevenindevelopedcountriesonlyasmallsimplynotknownatthegloballevel.Yet,HCVisnumberofthesearetreated.entirelypreventableandlargelycurable.Inordertoinvestigatetheexte
5、ntoftheAdiseasespreadthroughblood-to-bloodcontact,healthchallengeposedbyHCV,theEconomistHCVisusuallysymptomlessfordecades,alltheIntelligenceUnit,onbehalfofJanssen,whileslowlydamagingtheliver.Itisalreadyconducted16in-depthinterviewswithexperts,oneoftheworld
6、’sleadingcausesofcirrhosisincludingglobalandnationalhealthofficials,andprimarylivercancer–aformofthediseaseactivists,researchersandmedicalpersonnel,aswithespeciallylowsurvivalrates.HCVisalsowellasextensivedeskresearch.thebiggestreasonforlivertransplantsglo
7、bally,anoperationwhichrunsintohundredsofThekeyfindingsofthisresearchincludethethousandsofdollars,providedthereactuallyisfollowing:areplacementorganavailable.Worsestill,thetransplantisonlyatemporaryfix–reinfectionisThescopeoftheproblemisunknownbecauseuniver
8、sal.TherecurrenceofHCVinfectionafterepidemiologicaldataremainincomplete.livertransplantationleadstothedevelopmentAsoneofficialinterviewedforthisstudynoted,ofchronichepatitisinatleast50%ofgrafts“wedon’thaveare
