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1、Injury,Int.J.CareInjured42(2011)591–598ContentslistsavailableatScienceDirectInjuryjournalhomepage:www.elsevier.com/locate/injuryMasquelettechniqueforthetreatmentofbonedefects:Tips-tricksandfuturedirectionsPeterV.Giannoudis*,OmarFaour,ThomasGoff,NikolaosKanakaris,R
2、ozaliaDimitriouAcademicDepartmentofTraumaandOrthopaedicSurgery,LeedsNIHRBiomedicalResearchUnit,ClarendonWing,FloorA,GreatGeorgeStreet,LeedsGeneralInfirmary,LeedsLS13EX,UKARTICLEINFOABSTRACTArticlehistory:Reconstructionofdiaphysealbonedefectsstillrepresentsamajorcli
3、nicalchallenge.SeveralapproachesAccepted17March2011areusedwiththecommonobjectivetoregeneratebonelossandrestorefunction.ThemethodsmostcommonlyusedarethevascularisedfibulaautograftandtheIlizarovbonetransfertechnique.Recently,Keywords:Masqueletproposedaprocedurecombin
4、inginducedmembranesandcancellousautografts.TheaimofBonedefectthisarticlewastobrieflydescribethetechnique,toreviewthecurrentevidenceandtodiscussthetipsGrowthfactorsandtricksthatcouldhelpthesurgeonstoimproveoutcome.FuturedirectionstoincreaseitsInducedmembraneeffectiv
5、enessandexpanditsapplicationarealsobeingdiscussed.However,predictingtheoutcomeofBonerepairreconstructionofbonedefectsremainsdifficult;andthepatientshouldalwaysbeinformedthat,althoughpotentialcomplicationsaremostlypredictable,inmostofthecasesthereconstructionprocess
6、islonganddifficult.ß2011ElsevierLtd.Allrightsreserved.Introductionbeenirradiatedorinfected,providedthatanenvelopeispreviously6,7createdtoprotectandrevascularisethebonegraft.ReconstructionofdiaphysealbonedefectsstillrepresentsaThepurposeofthispaperistosuccinctlydesc
7、ribethemajorchallenge.Severalapproachesareusedinbonereconstruc-Masquelettechnique,toevaluatethecurrentevidencebytionwiththecommonobjectivetoregeneratebonelossandreviewingtherelevantanimalandclinicalstudies,andtodiscussrestorefunction.However,itisdifficulttoachievet
8、heseobjectivesusefultipsandtricksfromourownclinicalexperience.Futureinsomepathologicalsituations,suchaswhenalargebonedefectisdirectionsfortheuseofthiste
