Two hundred exercises in mechanistic organic chemistry

《Two hundred exercises in mechanistic organic chemistry》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、TwoHundredExercisesinMechanisticOrganicChemistry©GalChimia,S.L.,2004TwoHundredExercisesinMechanisticOrganicChemistryGabrielTojoSuárezProfesorTitulardeQuímicaOrgánicaUniversityofSantiagodeCompostelaqogatojo@uscmail.usc.es45PrefaceLearningthemechanisticbasisofO

2、rganicChemistryislikemasteringchess.Inthisgame,oneneedstoknowhowtomovethepiecesbeforeembarkinginamatch.Similarly,astudentinOrganicChemistrybeginsbylearningalistofsimplereactions.Thisallowsatalaterstagetoexplainthecomplexmechanismsthatinterveneinmanyorganicrea

3、ctionsandconsistinachainofsimplereactionsoperatinginasequentialway.ThisbookisaimedatstudentswhohavecompletedalearningcycleofOrganicChemistryandneedtosettletheirmechanisticknowledge.Oneofthesestudentsshouldbeabletosolveeachprobleminabouthalfanhour.AbachelorofO

4、rganicChemistryshouldbeabletodoitinabouttenminutes,whileaprofessionalOrganicChemistshouldconsumelessthantwominutes.Thereisnowaytoscientificallyprovethatacertainmechanismiscorrect.Amechanismcanonlybeprovedwrong.Mechanismsadmittedascorrectarethosethatexplainthe

5、experimentaldataandhavebeenabletoresistallattemptsatprovingtheirfalsehood.Ontheotherhand,onlyafewsimplereactionshavebeenstudiedindetailfromthemechanisticpointofview.Thereactionsdepictedinthisbookarecomplex,andnonehavebeenstudiedindetail.Consequently,thepropos

6、edsolutionsrepresenttheopinionofauthor.Proposingareasonablemechanismismorerelevantthanhittingtherightone.Manyexercisesadmitmorethanonesensiblemechanismandtheproposedsolutionsrepresentreasonable,butnotunique,answers.Noenterprisewouldmeetanendifthegoalistheperf

7、ection.Itisbettertomakesoonagoodjobthanneveraperfectone.Manypeoplewaitfortheperfectmomenttohavechildreninordertogivethemthebestpossibleeducation.Oftentheresultingdelaycausesthemtobebiologicallyunabletobeparents.Bearinginmindthathavingchildrenissosatisfactoryt

8、hatitiswortheveninaveryimperfectway,Ihavewrittenthisbook.Ihopetobeabletobeproudofthisintellectualoffspringinspiteofitsdeficiencies.Santiago,May20th2002GabrielTojo67ContentsABBREVIATIONS..