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1、裂隙灯图像分析系统联介荧光索钠在下眼诊断中的临床应用［摘耍］冃的:探讨使用裂隙灯图像分析系统定量分析联合荧光素的方法在眼科干眼诊断屮的应用。方法：干眼患者23例(23眼)为实验纟H.,眼部健康者29例(29眼)为对照组，分别于眼结膜囊内滴1%荧光素钠液，后应用数码照相机在裂隙灯显微镜下对检杳者眼前节进行拍照，从数码图像中提取泪河图像并用裂隙灯&用图像分析软件测量其高度，分析两组间下泪河高度的差别，以及下泪河高度与泪液分泌试验的相关性。结果：対照组和实验组的平均泪河高度分别是(0.25±0.05)伽及(0
2、.16±0.05)mm,差异有统计学意义(P<0.05)；干眼纟R泪河高度与泪液分泌试验具有显著相关性(-0.72,P<0.05)o结论：裂隙灯图像分析系统可用来测虽泪河高度，该项新技术可被用于干眼的诊断。［关键词］裂隙灯图像分析系统；荧光素钠；于眼；泪河高度［中图分类号］R77［文献标识码］C［文章编号］1674-4721(2011)08(b)-103-02Applicationofsiit-lampimageanalysissystemandf1uorcscein-sodiumindryeyeYAN
3、GChengmingl,ZENGQingguo2,BAOWeiguangl1.DepartmentofOphthalmology,XiliPeoplezsHospitalofNanshanDistrict,ShenzhenCity,GuangdongProvince,Shenzhen518055,China;2・DepartmentofPharmacy,XiliPeople'sHospitalofNanshanDistrict,ShenzhenCity,GuangdongProvince,Shenzhc
4、?n518055,China［Abstract］Objective:Todescribeamethodofquantifyingthetearmeniscusheight(TMH)andusingthesevaluestodiagnosepatientswithdryeye.Methods:23caseswithdryeye(23eyes)fortheexperimentalgroup,eyehealthwere29cases(29eyes)forthecontrolgroup,respectively
5、,intheconjunctivaoftheeyedropsof1%fluoresceinsodiumsolution,aftertheapplicationofdigitalcamerasintheslitlampmicroscopeanteriorsegmenloftheexaminertotakephotographs,digitalimagesextractedfromthetearmeniscusimageandimageanalyzedsoftwarededicatedslitlamptom
6、easuretheheightoftheanalyzeoftworiverheightdifferencebetweenthetears,andtearstheriverheightandSchirmertostthecorrelation.Results:Themeanvalueofthe1owertearmeniscusheightincontrolsubjectsandexperimcntgroupwere0.25mmand0・16mmrespectively.Showingsignificsnt
7、statisticaldiffereneebetweenthetwogroups(P<0.05).Asignificantcorrelationwasalsofoundbetweenthelowertearlowermeniscusheightandschirmertestvalues(r二0.72,P〈0.05)-Conelusion:Fluorescoin-sodiumphotographsoftheeyecanbeusedtoquantifythelowertearmoniscusheight・T
8、histechniquecanbeusedforthediagnosisofdryeye・［Keywords］SIit-lampimageprocessing;Fluorescein-sodium;Dryeye;Tearmeniscusheight干眼是眼科门诊的常见病及多发病，是由于泪液的质或量异常引起泪膜不稳定和眼表损害所导致的最常见的眼表疾病Z—［1］。泪河是指人的泪液在脸缘和眼球表面Z间形成新月面，其中脂质层是形成泪河表面的基础。裂
