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1、海普林软膏治疗硬皮病的临床效果评价【摘要】目的：研究应用海普林软膏对患有硬皮病的患者实施治疗的临床效果。方法：选择2012年7月-2014年7月在本院就诊患有硬皮病的78例患者作为研究对象，按照随机数字表法将英分为対照组和治疗组，每组39例。对照组采用常规药物进行治疗，治疗组在常规药物治疗的基础上加用海普林软膏。观察比较两组患者的皮肤外观恢复正常时间和硬皮病治疗计划实施总时间、硬皮病治疗效果及药物不良反应发生情况。结果：经治疗后，治疗组的皮肤外观恢复正常时间和硬皮病治疗计划实施总时间均明显短于对照组，
2、治疗总有效率92.3%明显高于对照组的71.8%,药物不良反应发生率2.6%明显低于对照组的20.5%,比较差异均冇统计学意义(P<0.05)o结论：应用海普林软膏对患有硕皮病的患者实施治疗的临床效果显著，值得临床推广应用。【关键词】海普林软膏；硬皮病；治疗ClinicalEffectEvaluationofHepudiod()intmentintheTreatmentofScleroderma/LIUShi,ZHANGDong-xing,LILing.//MedicalInnovationofChi
3、na,2015,12(23)：109-110【Abstract】Objective：TostudytheclinicaleffectofHepudiodOintmentinthetreatmentofpatientswithscleroderma.Method：78patientswithsclerodermaadmittedtoourhospitalfromJuly2012toJuly2014wereselectedasresearchobjects，theyweredividedintotheco
4、ntrolgroupandthetreatmentgroupaccordingtotherandomnumbertablemethod,39casesineachgroup.Thecontrolgroupwastreatedwithconventionaldrugs,thetreatmentgroupwastreatedwithHepudiodOintmentonthebasisofconventionaldrugtreatment・Thetimeoftheskinappearancereturnst
5、onormalandthetotaltimeoftreatmentplanofscleroderma,sclerodermatreatmenteffectandadversedrugreactionsbetweenthetwogroupswereobservedandcompared.Result:Thetimeoftheskinappearancereturnstonormalandthetotaltimeoftreatmentplanofsclerodermainthetreatmentgroup
6、weresignificantlyshorterthanthecontrolgroup,thetotaleffectiverateofthetreatmentgroupwas92.3%,whichwassignificantlyhigherthan71.8%ofthecontrolgroup,theincidenceofadversedrugreactionsinthetreatmentgroupwas2.6%,whichwassignificantly1owerthan20.5%inthecontr
7、olgroup,thedifferenceswerestatisticallysignificant(P<0.05)•Conclusion：TheclinicaleffectofHepudiodOintmentinthetreatmentofpatientswithsclerodermaissignificant,isworthyofclinicalpopularizationandapplication.【Keywords】HepudiodOintment；Scleroderma；Treatment
8、First-authorsaddress：ThePeople,sHospitalofMeizhouCity,Meizhou514023,Chinadoi：10.3969/j.issn.1674-4985.2015.23.038硕皮病是比较常见的一种皮肤病，在临床上乂被称为硕斑病，是限局性皮肤肿胀的一种，该类患者的皮肤会逐渐发生硬化萎缩［1］。局部皮肤红肿是硬皮病在发展期的主要症状表现，且皮肤的温度会明显偏高，病变面积在近期内会有明显的扩大，同时伴随出现皮
