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1、进展型脑梗死的临床治疗分析［摘耍］冃的：探讨低分子肝素钙和降纤酶联合治疗进展型脑梗死的疗效。方法：将我院收治的60例进展型脑梗死患者随机分为治疗组及对照组，对照组应用低分了肝素钙，观察组在对照组基础上加用降纤酶。结果：治疗组基本治愈和显著进步的例数明显多于对照组，差杲有统计学意义(PV0.05)；两组治疗前后神经功能评分和日常生活能力评分均有显著性改善，差界有统计学意义(PV0.05),治疗组改善更加明显，优于対照组，差界有统计学意义(P<0.05)；治疗组发生1例再梗死,占总例数的3.33%,对照组5例再次梗死,占总例数的16.67%,差异有统计学意义
2、(PV0.05)。两组均无严重出血性并发症。结论：应用低分了肝索鈣和降纤酶联介治疗进展型脑梗死早期效果显著，能改善神经功能缺损，提高LI常生活能力，明显降低致残率，同吋其副反应较小，值得临床推广。［关键词］进展型脑梗死；低分子肝索钙；降纤酶［中图分类号］R743.33［文献标识码］A［文章编号］1673-7210(2009)01(b)-036-02ClinicaltreatmentanalysisofprogressivecerebralinfarctionLTYu-wang(HuanhuHospitalofTianjinCity,Tianjin0300
3、60,China)［Abstract］Objective:Todiscusstheclinicaleffectof1ow-mo1ecu1ar-weightheparincombinedwithdefibraseinthetreatmentofprogressivecerebralinfarction.Methods:60casesofprogressivecerebralinfarctionpatientswererandomlydividedintotreatmentgroupandcontrolgroup.Controlgroupused1owmo1
4、ecu1ar-weightheparin,treatmentgroupuseddefibraseadditionally.Results:Casesofbasiccureandsignificantprogressintreatmentgroupweresignificantlymorethancontrolgroup,therewasasignificantdiffercnccbetweentwogroups(P<0・05);neurologicalscoreandthescoreofdailylivingsignificantlyimprovedbe
5、foreandaftertreatmentinbothtwogroups,therewasasignificantdifferenee(P<0.05);thescoreintreatmentgroupimprovedmoreobviousthancontrolgroup,therewasasignificantdifference(P〈0.05);re-infarctionoccurredin1caseintreatmentgroup(3.33percenl),5caseincontrolgroup(16.67percent),therewasasign
6、ificantdifference(P〈0.05).Noseverebleedingcomplicationsoccured.Conelusion:Combinationof1ow-mo1ecu1ar-weightheparinwithdefibrasehadobviouseffectinthetreatmentofearlystageofprogressivecerebralinfarction,canimprovetheneurologicalimpairment,increasetheactivityofdailyliving,significan
7、tlyreducedisabi1ity,atthesametime,itssideeffectisless,worthytobepopularized.［Keywords］Progressivecerebralinfarction;Lowmo1ecu1ar-weightheparin;Defibrase脑血管病是老年人常见病和多发病，进展型脑楝死是指缺血发病6h后，局灶神经功能缺损症状进行性加重的脑梗死，>50%是在病初24h内出现的［1］,治疗比较困难，神经功能恢复较差，严重危害患者的身心健康和生活质量。我院于2004年1月〜2007年1月在常规治疗基
8、础上应用低分了量肝素和降纤酶联合治疗进展型脑梗死，效果满意，现报道如下：1资料与
