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1、舒利迭治疗COPD缓解期34例疗效观察［摘要］目的探讨舒利迭治疗慢性阻塞性肺疾病（COPD）缓解期的临床疗效。方法将68例住院COPD缓解期患者随机分为治疗组和对照组。对照组患者予以COPD常规治疗，包括低流量持续吸氧，预防感染，常规服用氨茶碱，增强机体免疫力，吸入异丙托漠镀,呼吸肌锻炼及按需使用沙丁胺醇。治疗组在对照组治疗的基础上加用舒利迭粉吸入剂，1吸/次,1次/d,每次2喷。两组患者疗程均为3个月。结果治疗组总有效率为88.24%,对照组总有效率为67.65%,两组总有效率比较差异有统计学意义（P<0.05）b治疗后治疗组患者的用力肺活量（FVC,第一秒用力呼气容积（FEV
2、1）及FEV1/FVC均明显优于对照组，差异有统计学意义（P<0.05）;治疗后治疗组患者的动脉血氧分压（PaO2X二氧化碳分压（PaCO2）均明显优于对照组,差异有统计学意义（P<0.05）b结论舒利迭吸入是COPD缓解期患者的一种有效、安全的治疗方法。［关键词］慢性阻塞性肺疾病；舒利迭；肺功能［中图分类号］R563.1［文献标识码］A［文章编号］1673-7210(2012)01(c)-0079-03ObservationofcurativeeffectsonSeretideinthetreatmentof34patientswithchronicobstructivepul
3、monarydiseaseofremissionphaseWANGZhengweiWEILipingHEShengCAIYaoquanDepartmentofRespiration,theThirdAffiliatedHospitalofGuangzhouMedicalCollege,GuangdongProvinee,Guangzhou510150,China[Abstract]ObjectiveToinvestigatethecurativeeffectsofSeretideinthetreatmentofpatientswithchronicobstructivepulmo
4、narydisease(COPD)ofremissionphase.Methods68hospitalizedpatientsintheCOPDremissionphasewererandomlydividedintotreatmentgroupandcontrolgroup.ThecontrolgroupreceivedCOPDconventionaltreatment,includinguptakeoflow-flowcontinuousoxygen,preventionofinfection,routineadministrationofaminophylline,incr
5、easeofbodyimmunity,inhalationofipratropiumbromide,trainingofrespiratorymuscleandon-demanduseofsalbutamol.Thetreatmentgroupreceivedadditionalseretidepowderinhalant1inhalationeverytime,onceadayand2prayseverytimeonthebasisofconventionaltreatment.Thetreatmentcourseforbothgroupswas3months.ResultsT
6、hetotaleffectiveratewas88.24%inthetreatmentgroupandthetotaleffectiveratewas67.65%inthecontrolgroup,withstatisticallysignificantdifferencebetweenthetwogroups(P<0.05).Aftertreatment,thetreatmentgroupwassuperiortothecontrolgroupinforcedvitalcapacity(FVC),forcedexpiratoryvolumein1second(FEV1)andF
7、EV1/FVC,withstatisticallysignificantdifferences(P<0.05).Aftertreatment,thetreatmentgroupwassuperiortothecontrolgroupinPaO2andPaCO2,withstatisticallysignificantdifferences(P<0.05).ConclusionSeretideinhalationisasafeandeffectivetherapyforpatien
