艾塞那肽治疗2型糖尿病的疗效观察

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1、中国医科大学硕士学位论文艾塞那肽治疗2型糖星病的疗效观察姓名：许多申请学位级别：硕士专业：临床医学；内科学指导教师：李玲201203和輛輛静奉酬躺瞬购枷輔輔稀輪赫删芟麴肽繃疗,碱畑卿洞嘶諏锲方懣财omm、<»科映脯啊，制勲患跚俪为鹼師辦鱷力住慎懂储誠2甌職甌*臨«!矚舖眦红剧螺歸鹅Bit不良反应发生情况。研究期闸統懸甫删嘶醐撚矢逋叙礎叮歸攝椰匡邛辅躺豁翩郷W-Sllli艮査体重、血压、空殿査空腹血清胰岛素；1EJ001),佩删懈滄疗后21枸月傭看P哄堀稠枷侃曲率疏利總沁泌&HQMAt

2、树諾前6个刀变化开统计学意义，M12个月时明显升高（P<0.001）•患者■治疗期间体重和BMI进彳亍性下降・騒化驰制聽4T（爲弼;雛輙tW鋅牌W翩！进行性下降’嚟淼1爺料羈薔聪镰肠翳製黔艇絆痢軽於騎°，018）>鹦鯛蹄翩餐磁询斛掷跚麴或烝縱％髏鼬船陆鯛泊隔瞬讎磁彩瀛撅表示无恶心，仅有轻度的食欲减追并持续存在。12个月期间无低血糖或急件胰腺炎发生。绩论结论这一研究显示，GLP-1类似物应用于血糖控制不佳的2型糖尿病患者可以这，缈蛰运；CLP.丄审/媲也田盂翊抢亂不佳的2熨糖尿病患者可以有效地达到血糖控制目枫同时可以达到控制体重仙目的。

3、有效地达到血糖控制日标，同时可以达到控制体匝的H的。发生。芙键词辺塑撕溺輪;艾瘗娜脈见A%体車：体亟•英文论著摘要・Clinicalshe:tudyoftefficacyofeXenheatideint财pe2diabetesme11itus0bjectiveTop&ticntswimtype2iitbetesiitheapplicationoftheoriginal(Jra1glDton-hvtriijdruipoorbloodglicojecontrolanduscofaiplugthatpeptidetreatment,obse

4、rvetheaiplugpeptidestype2diabetescurativeefResearculjjet

5、andmethodh•pltiiOHwimtype2diabetesmellitusreceivedExenatidetherapylastatleast4months・BloodglucoselevelandIIbA1Candbodyweightwererecorded・After12monthtnalUMlFPG,2hPGandHbAIclereduced(P<0.05),veIisfoundn1atH0MA—IRha

6、vestatisticallyreduced(P=O.022),HOMA—risingBissignificantly(P<0.001)ithereisBMIstatisticalsignificance(P<0.Q5).Tpatientsrarelyappeargastrointestinalsymptoms,malenotobvious・°nTostIyrisingandthehypo^ycemiaandpancreatitistheotherindexisnottreatment,sboblflertreitnent,isnoi

7、inifitulpphanges・NoConclusionPatientswithtype2diabetesme1IitcanauswhieveoptimalglycemicthdIkerapjiiiUthebodyweight・Keywordstype•英文论著摘要•3Clinicalstudyoftheefficacyofexenatideinthetype2diabetesmellitusObjectiveTopatientswithtype2diabetesintheapplicationoftheoriginaloralgl

8、ucose-loweringdrugs,poorbloodglucosecontrolanduseofaiplugthatpeptidetreatment,observetheaiplugpeptidestype2diabetescurativeeffectResearchobjectandmethod30patientswithtype2diabetesmellitusreceivedExenatidetherapylastatleast4months.BloodglucoselevelandHbAlCandbodyweightwe

9、rerecorded.ResultsAfter12monthstreatmentFPG,2hPGandHbAlclevelisreduced(P<0.05),foundthatHOMA-IRhavestatistical