[精品]原发性头痛与焦虑抑郁的关系及抗焦虑抑郁治疗的效果.doc

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1、原发性头痛与焦虑抑郁的关系及抗焦虑抑郁治疗的效果原发性头痛与焦虑抑郁的关系及抗焦虑抑郁治疗的效果［摘耍］目的探讨原发性头痛与焦虑抑郁的关系及抗焦虑抑郁治疗的效果。方法选取2012年1月〜2014年1月本院收治的100例原发性头痛患者，依据随机数字表法将患者分为观察组、对照组,每组各50例。对照组患者给予盐酸氟桂利嗪胶囊治疗，观察组患者在对照组基础上给予氟哌曝吨美利曲辛片治疗。结果治疗前，两组患者的HADS.NRS评分比较，差异均无统计学意义(P〉0・05)；治疗后2、4周，观察组患者的H/DS、NRS评分均明显比对照组低(P〈

2、0・05)。治疗后2周，观察组、对照组患者的头痛减轻有效率分别为32%(16/50)、20%(10/50),两组比较，差异无统计学意义(P>0.05)；治疗后4周，观察组患者的头痛减轻有效率为66%(33/50),明显高于对照组的36%(18/50)(P<0.05)o结论原发性头痛与焦虑抑郁密切相关，抗焦虑抑郁治疗的效果显著。［关键词］原发性头痛；焦虑抑郁；关系；抗焦虑抑郁治疗［中图分类号］R441.1［文献标识码］B［文章编号］1674-4721(2014)09(c)-0164-03Correlationbetweenprim

3、aryheadacheandanxiety,depress!onandeffectofanti~anxietydepress!ontreatmentCHENDong-liDepartmentofNeurology,BeijingShunyiAirportHospitai,Beijing101312,China［Abstract］ObjectiveToinvestigatethecorrelationbetweenprimaryheadacheandanxiety,depressionandeffectofanti-anxiety

4、depressiontreatment・Methods100caseswithprimaryheadacheinourhospitalfromJanuary2012toJanuary2014wereselected,thesepatientsweredividedintotheobservationgroup(n=50)andthecontrolgroup(n二50)accordingtotherandomnumbertable.Patientsinthecontrolgroupweretreatedwithfilmarizin

5、ehydrochloridecapsule,patientsintheobservationgroupweretreatedwithflupentixolandmelitracentabletonthebasisofthecontrolgroup・ResultsTherewasnostatisticaldifferenceofHADS,NRSscorebeforetreatmentbetweenthetwogroups(P>0.05),andHADS,NRSscoreafter2and4weekstreatmentoftheob

6、servationgroupweresignificantlylowerthanthoseinthecontrolgroup(P<0.05)・Theeffectiverateofheadacheeasingafter2weekstreatmentintheobservationgroupandthecontrolgroupwas32%(16/50),20%(10/50)respectively,andtherewasnostatisticaldifferenceinthetwogroups(P>0.05)；after4weeks

7、treatment,theeffectiverateofheadacheeasingintheobservationgroup[66%(33/50).wassignificantlyhigherthanthatinthecontrolgroup[36%(18/50)](P<0.05).ConclusionPrimaryheadacheiscloselyrelatedtoanxiety,depression,theeffectofanti-anxietydepressiontreatmentisremarkable・[Keywor

8、ds]Primaryheadache；Anxietyanddepression；Correlation；Anti-anxietydepressiontreatment在神经科临床中，头痛是一，种极为常见的症状，多数患者在既往丰活史中有焦虑抑郁情绪，而焦虑抑郁情绪