资源描述：
《国产与进口鲑鱼降钙素治疗PMOP的疗效与经济比较.doc》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。
1、国产与进口鮭佝降鈣索治疗PMOP的疗效与经济比较［摘要］目的比较国产与进口鮭鱼降钙素治疗绝经后骨质疏松症(postmenopausalosteoporosis,PMOP)的疗效及经济。方法60例PMOP患者分成观察组和对照组。对照组：进口鮭曲降钙索注射液+维生索D钙咀嚼片；观察组：国产鮭鱼降钙索注射液+维生索D鈣咀嚼片。结果对照组显效率60.00%、有效率30.00%、无效率10.00%,与观察组显效率56.67%、有效率36.67%.无效率6.67%比较，茅异均无显著性(P>0.05)；治疗前与治疗示两组患者骨密度比较，差异
2、无显著性(P>0.05)；两组不良反应发生率差异无显著性(P>0.05)o国产鮭鱼降钙素注射液价格要明显低于进口鮭鱼降钙素注射液。结论国产鮭鱼降钙素注射液联合维生素D钙咀嚼片治疗PMOP患者疗效可靠、安全，而且经济实惠，值得临床应用推广。［关键词］绝经后骨质疏松症；鮭鱼降钙素；国产；进口；维生素D钙咀嚼片［屮图分类号］R580［文献标识码］B［文章编号］1673-9701(2011)24-91-02CurativeEffectandEconomicComparisonbetweenDomesticandImportSalmon
3、CalcitonininTreatmentofPMOPIIUJingyanEndocrineDivisionofYinzhouPeople'sHospital,Ningbo315040,China［Abstract］ObjectiveTocomparethecurativeeffectandeconomicbetweenDomesticandImportsalmoncalcitoninIreatmontofpostmenopausalosteoporosis(PMOP)・MethodsAll60casesofPMOPdivid
4、edintoobservationgroupandcontrolgroup.Controlgroup：Importsalmoncalcitonin+calciumsupplementwithVitaminDchewabletablets；ObservationGroup：Domesticsalmoncalcitonin+calciumsupplementwithVitaminDchewabletablets.ResultsThecontrolgroup：significantefficiency,efficient,ineff
5、icientwere60.00%,30.00%,10.00%,respectively；Theobservationgroup：significantefficiency,efficient,inefficientwere56.67%,36.67%,6.67%,respectively.Therewasnosignificantdiffereneebetweentwogroups(P>0.05)•Beforetreatmentandtherapycomparedwithaftertreatment，therewasnosign
6、ificancediffereneeinBMDbetweentwogroups(P>0.05)・Adversereactionrateoftwogroupswasnosignificantdifference(P>0.05)・Domesticsalmoncalcitonininjectionpricewascheaperthanimportedsalmoncalcitonininjection.ConclusionDomesticsalmoncalcitoninandcalciumsupplementwithVitaminDc
7、hewabletabletstreatmentofPMOPisgoodefficacy,feweradversereactions,affordable.［Keywords］Postmenopausalosteoporosis；Salmoncalcitonin；Domestic；Import；CalciumsupplementwithVitaminDchewabletablets绝经示骨质疏松症(PostmenopEmsalosteoporosis,PMOP)是指绝经后妇女发生的以低骨量及骨纟fl织微结构退行性病变为特征的一种
8、全身性骨骼疾病。有研究报道鮭鱼降钙素在治疗骨质疏松症方面疗效较佳［1］,但鮭鱼降钙素的生产，国内外有不同的厂家。木课题屮笔者在维生索D钙咀嚼片用药基础上，分别加用国产鮭鱼降钙索注射液(桂林南药股份有限公司)和进口鮭鱼降钙素注射液(瑞士诺华制药有限公司)治疗PMOP,并对其疗效
